I am sorry for you tonight, Mr. President. You are facing one of the greatest decisions of your career. Upon what you decide depends on whether or not you are going to get your canal. If you fall back upon the old methods of sanitation you will fail, just as the French failed. If you back up Dr. Gorgas and his ideas, and you let him make his campaign against mosquitoes, then you get your canal. I can only give you my advice; you must decide for yourself. There is only one way of controlling yellow fever and malaria, and that is the eradication of the mosquitoes. But it is your canal; you must do the choosing and you must choose tonight whether you are going to build that canal.

But such is the nature of man that as soon as you begin to force him to do a thing, from that moment he begins to seek ways by which he can avoid doing the thing you are trying to force upon him. A man with malaria parasites in his blood is a danger to his companions. To kill all the parasites, he was then required to continue doses of quinine a week or ten days after his fever. When the convalescing men were given their daily dose of quinine they would manage to throw their tablets out of the dispensary window. The old turkey-gobbler pet of the hospital gobbled up all the tablets he could find. He became so dissipated he finally developed a species of blindness caused by too much quinine. I cannot vouch for this, but I was often twitted with this story as an illustration of how the men were treating prophylactic quinine.