To suppose that the eye with all its inimitable contrivances for adjusting the focus to different distances, for admitting different amounts of light, and for the correction of spherical and chromatic aberration, could have been formed by natural selection, seems, I confess, absurd in the highest degree...The difficulty of believing that a perfect and complex eye could be formed by natural selection , though insuperable by our imagination, should not be considered subversive of the theory.

In science's pecking order, evolutionary biology lurks somewhere near the bottom, far closer to phrenology than to physics. For evolutionary biology is a historical science, laden with history's inevitable imponderables. We evolutionary biologists cannot generate a Cretaceous Park to observe exactly what killed the dinosaurs; and, unlike "harder" scientists, we usually cannot resolve issues with a simple experiment, such as adding tube A to tube B and noting the color of the mixture.

Genetics might be adequate for explaining microevolution, but microevolutionary changes in gene frequency were not seen as able to turn a reptile into a mammal or to convert a fish into an amphibian. Microevolution looks at adaptations that concern the survival of the fittest, not the arrival of the fittest... The origin of species — Darwin’s problem — remains unsolved.

No fossil is buried with its birth certificate. That, and the scarcity of fossils, means that it is effectively impossible to link fossils into chains of cause and effect in any valid way... To take a line of fossils and claim that they represent a lineage is not a scientific hypothesis that can be tested, but an assertion that carries the same validity as a bedtime story—amusing, perhaps even instructive, but not scientific.

The idea that one can go to the fossil record and expect to empirically recover an ancestor-descendant sequence, be it of species, genera, families, or whatever, has been, and continues to be, a pernicious illusion.

For those scientists who take it seriously, Darwinian evolution has functioned more as a philosophical belief system than as a testable scientific hypothesis. This quasi-religious function of the theory is, I think, what lies behind many of the extreme statements that you have doubtless encountered from some scientists opposing any critical analysis of neo-Darwinism in the classroom. It is also why many scientists make public statements about the theory that they would not defend privately to other scientists like me.

The phrase 'the fossil record' sounds impressive and authoritative. As used by some persons it becomes, as intended, intimidating, taking on the aura of esoteric truth as expounded by an elite class of specialists. But what is it, really, this fossil record? Only data in search of interpretation. All claims to the contrary that I know, and I know of several, are so much superstition.

The ideology and philosophy of neo-Darwinism which is sold by its adepts as a scientific theoretical foundation of biology seriously hampers the development of science and hides from students the field’s real problems.

That natural selection can produce changes within a type is disputed by no one, not even the staunchest creationist. But that it can transform one species into another — that, in fact, has never been observed.

Throughout 150 years of the science of bacteriology, there is no evidence that one species of bacteria has changed into another... Since there is no evidence for species changes between the simplest forms of unicellular life, it is not surprising that there is no evidence for evolution from prokaryotic [i.e., bacterial] to eukaryotic [i.e., plant and animal] cells, let alone throughout the whole array of higher multicellular organisms.

I recently asked more than seventy eminent researchers if they would have done I their work differently if they had thought Darwin's theory was wrong. The responses were all the same: no. I also examined the outstanding biodiscoveries of the past century: the discovery of the double helix; the characterization of the ribosome: the mapping of genomes; research on medications and drug reactions: improvements in food production and sanitation; the development of new surgeries; and others. I even queried biologists working in areas where one would expect the Darwinian paradigm to have most benefited research, such as the emergence of resistance to antibiotics and pesticides. Here, as elsewhere, I found that Darwin's theory had provided no discernible guidance, but was brought in, after the breakthroughs, as an interesting narrative gloss.

I am absolutely convinced of the lack of true scientific evidence in favour of Darwinian dogma. Nobody in the biological sciences, medicine included, needs Darwinism at all. Darwinism is certainly needed, however, in order to pose as a philosopher, since it is primarily a worldview. And an awful one, as George Bernard Shaw used to say.

All disciplines of science are built on the causality of the relationships governing related events. Yet the theory of evolution is built upon the idea of accidental changes that resulted in complex living systems. I was unable to comprehend how the notion that an infinite number of random accidents systematically happened to produce living species, and kept improving these beings, is justified.

Evolution is promoted by its practitioners as more than mere science. Evolution is promulgated as an ideology, a secular religion -- a full-fledged alternative to Christianity, with meaning and morality. I am an ardent evolutionist and an ex-Christian, but I must admit that in this one complaint -- and Mr. Gish [Duane T. Gish the Creation Scientist] is but one of many to make it -- the literalists are absolutely right. Evolution is a religion. This was true of evolution in the beginning, and it is true of evolution still today.

I myself am convinced that the theory of evolution, especially to the extent to which it has been applied, will be one of the greatest jokes in the history books of the future. Posterity will marvel that so very flimsy and dubious an hypothesis could be accepted with the incredible credulity it has.

In the last 25 years, criticism of most theories advanced by Darwin and the neo-Darwinians has increased considerably, and so did their defense. Darwinism has become an ideology, while the most significant theories of Darwin were proven unsupportable. The critics advanced other theories instead of 'natural selection' and the survival of the fittest'. 'Saltatory ontogeny' and 'epigenesis' are such new theories proposed to explain how variations in ontogeny and novelties in evolution are created. They are reviewed again in the present essay that also tries to explain how Darwinians, artificially kept dominant in academia and in granting agencies, are preventing their acceptance. Epigenesis, the mechanism of ontogenies, creates in every generation alternative variations in a saltatory way that enable the organisms to survive in the changing environments as either altricial or precocial forms. The constant production of two such forms and their survival in different environments makes it possible, over a sequence of generations, to introduce changes and establish novelties--the true phenomena of evolution. The saltatory units of evolution remain far-from-stable structures capable of self-organization and self-maintenance (autopoiesis).[Evolution by epigenesis: farewell to Darwinism, neo- and otherwise.]

To understand Darwin's work, you have to distinguish between his theory of descent and his theory of natural selection. THe full name of the first is the theory of descent with modification. Some call it the fact of evolution, and some call it the doctrine of evolution.

I am suggesting here that organisms have a built-I capability of adapting to their environment. I am suggesting that to the extent that evolution occurs, it occurs at the level of the organism. This suggestion differs sharply from the thesis of the NDT, which holds that evolution occurs only at the level of the population. Organisms contain within themselves the information that enables them to develop a phenotype adaptive to a variety of environments. The adaptation can occur by a change in the genome through a genetic change triggered by the environment, or it can occur without any genetic change.

Verbal arguments should always be suspect.

Life is so diversified that to any statement I could make about living organisms there are exceptions. Because of the many exceptions, I should qualify everything I say with hedging phrases such as 'generally,' 'usually,' and 'almost always' But I'm afraid the constant repetition of these hedges will slow me down and bore you. So let's make a pact now that I forego the hedging phrases and you are to understand that almost all my statements may have rare exceptions.

Except for the rare cases of plastid inheritance, the inheritance of all known cofactors can be sufficiently accounted for by the presence of genes in the chromosomes. In a word the cytoplasm may be ignored genetically.