If this book has a lesson, it is that we are awfully lucky to be here-and by 'we' I mean every living thing. To attain any kind of life in this universe of ours appears to be quite an achievement. As humans we are doubly lucky, of course: We enjoy not only the privilege of existence but also the singular ability to appreciate it and even, in a multitude of ways, to make it better. It is a talent we have only barely begun to grasp.
Thus, from the war of nature, from famine and death, the most exalted object which we are capable of conceiving, namely, the production of the higher animals, directly follows. There is grandeur in this view of life, with its several powers, having been originally breathed into a few forms or into one; and that, whilst this planet has gone cycling on according to the fixed law of gravity, from so simple a beginning endless forms most beautiful and most wonderful have been, and are being, evolved.
Were these boys in their right minds? Here were two boys with good intellect, one eighteen and one nineteen. They had all the prospects that life could hold out for any of the young; one a graduate of Chicago and another of Ann Arbor; one who had passed his examination for the Harvard Law School and was about to take a trip in Europe,--another who had passed at Ann Arbor, the youngest in his class, with three thousand dollars in the bank. Boys who never knew what it was to want a dollar; boys who could reach any position that was to boys of that kind to reach; boys of distinguished and honorable families, families of wealth and position, with all the world before them. And they gave it all up for nothing, for nothing! They took a little companion of one of them, on a crowded street, and killed him, for nothing, and sacrificed everything that could be of value in human life upon the crazy scheme of a couple of immature lads.Now, your Honor, you have been a boy; I have been a boy. And we have known other boys. The best way to understand somebody else is to put yourself in his place.Is it within the realm of your imagination that a boy who was right, with all the prospects of life before him, who could choose what he wanted, without the slightest reason in the world would lure a young companion to his death, and take his place in the shadow of the gallows?...No one who has the process of reasoning could doubt that a boy who would do that is not right.How insane they are I care not, whether medically or legally. They did not reason; they could not reason; they committed the most foolish, most unprovoked, most purposeless, most causeless act that any two boys ever committed, and they put themselves where the rope is dangling above their heads....Why did they kill little Bobby Franks?Not for money, not for spite; not for hate. They killed him as they might kill a spider or a fly, for the experience. They killed him because they were made that way. Because somewhere in the infinite processes that go to the making up of the boy or the man something slipped, and those unfortunate lads sit here hated, despised, outcasts, with the community shouting for their blood.. . . I know, Your Honor, that every atom of life in all this universe is bound up together. I know that a pebble cannot be thrown into the ocean without disturbing every drop of water in the sea. I know that every life is inextricably mixed and woven with every other life. I know that every influence, conscious and unconscious, acts and reacts on every living organism, and that no one can fix the blame. I know that all life is a series of infinite chances, which sometimes result one way and sometimes another. I have not the infinite wisdom that can fathom it, neither has any other human brain
In every remote corner of the world there are people like Carl Jones and Don Merton who have devoted their lives to saving threatened species. Very often, their determination is all that stands between an endangered species and extinction.But why do they bother? Does it really matter if the Yangtze river dolphin, or the kakapo, or the northern white rhino, or any other species live on only in scientists' notebooks?Well, yes, it does. Every animal and plant is an integral part of its environment: even Komodo dragons have a major role to play in maintaining the ecological stability of their delicate island homes. If they disappear, so could many other species. And conservation is very much in tune with our survival. Animals and plants provide us with life-saving drugs and food, they pollinate crops and provide important ingredients or many industrial processes. Ironically, it is often not the big and beautiful creatures, but the ugly and less dramatic ones, that we need most.Even so, the loss of a few species may seem irrelevant compared to major environmental problems such as global warming or the destruction of the ozone layer. But while nature has considerable resilience, there is a limit to how far that resilience can be stretched. No one knows how close to the limit we are getting. The darker it gets, the faster we're driving.There is one last reason for caring, and I believe that no other is necessary. It is certainly the reason why so many people have devoted their lives to protecting the likes of rhinos, parakeets, kakapos, and dolphins. And it is simply this: the world would be a poorer, darker, lonelier place without them.
Thus, by science I mean, first of all, a worldview giving primacy to reason and observation and a methodology aimed at acquiring accurate knowledge of the natural and social world. This methodology is characterized, above all else, by the critical spirit: namely, the commitment to the incessant testing of assertions through observations and/or experiments — the more stringent the tests, the better — and to revising or discarding those theories that fail the test. One corollary of the critical spirit is fallibilism: namely, the understanding that all our empirical knowledge is tentative, incomplete and open to revision in the light of new evidence or cogent new arguments (though, of course, the most well-established aspects of scientific knowledge are unlikely to be discarded entirely).. . . I stress that my use of the term 'science' is not limited to the natural sciences, but includes investigations aimed at acquiring accurate knowledge of factual matters relating to any aspect of the world by using rational empirical methods analogous to those employed in the natural sciences. (Please note the limitation to questions of fact. I intentionally exclude from my purview questions of ethics, aesthetics, ultimate purpose, and so forth.) Thus, 'science' (as I use the term) is routinely practiced not only by physicists, chemists and biologists, but also by historians, detectives, plumbers and indeed all human beings in (some aspects of) our daily lives. (Of course, the fact that we all practice science from time to time does not mean that we all practice it equally well, or that we practice it equally well in all areas of our lives.)
There were long stretches of DNA in between genes that didn't seem to be doing very much; some even referred to these as "junk DNA," though a certain amount of hubris was required for anyone to call any part of the genome "junk," given our level of ignorance.
We gain from the new science of mind not only insights into ourselves - how we perceive, learn, remember, feel, believe and act - but also a new perspective of ourselves and our fellow human beings in the context of biological evolution.
The total amount of suffering per year in the natural world is beyond all decent contemplation. During the minute that it takes me to compose this sentence, thousands of animals are being eaten alive, many others are running for their lives, whimpering with fear, others are slowly being devoured from within by rasping parasites, thousands of all kinds are dying of starvation, thirst, and disease. It must be so. If there ever is a time of plenty, this very fact will automatically lead to an increase in the population until the natural state of starvation and misery is restored. In a universe of electrons and selfish genes, blind physical forces and genetic replication, some people are going to get hurt, other people are going to get lucky, and you won't find any rhyme or reason in it, nor any justice. The universe that we observe has precisely the properties we should expect if there is, at bottom, no design, no purpose, no evil, no good, nothing but pitiless indifference.
The following proposition seems to me in a high degree probable—namely, that any animal whatever, endowed with well-marked social instincts, the parental and filial affections being here included, would inevitably acquire a moral sense or conscience, as soon as its intellectual powers had become as well, or nearly as well developed, as in man. For, firstly, the social instincts lead an animal to take pleasure in the society of its fellows, to feel a certain amount of sympathy with them, and to perform various services for them.
To suppose that the eye with all its inimitable contrivances for adjusting the focus to different distances, for admitting different amounts of light, and for the correction of spherical and chromatic aberration, could have been formed by natural selection, seems, I confess, absurd in the highest degree...The difficulty of believing that a perfect and complex eye could be formed by natural selection , though insuperable by our imagination, should not be considered subversive of the theory.
To put it bluntly but fairly, anyone today who doubts that the variety of life on this planet was produced by a process of evolution is simply ignorant—inexcusably ignorant, in a world where three out of four people have learned to read and write.
In science's pecking order, evolutionary biology lurks somewhere near the bottom, far closer to phrenology than to physics. For evolutionary biology is a historical science, laden with history's inevitable imponderables. We evolutionary biologists cannot generate a Cretaceous Park to observe exactly what killed the dinosaurs; and, unlike "harder" scientists, we usually cannot resolve issues with a simple experiment, such as adding tube A to tube B and noting the color of the mixture.
Some people with Tourette's have flinging tics- sudden, seemingly motiveless urges or compulsions to throw objects..... (I see somewhat similar flinging behaviors- though not tics- in my two year old godson, now in a stage of primal antinomianism and anarchy)
I like to define biology as the history of the earth and all its life — past, present, and future. To understand biology is to understand that all life is linked to the earth from which it came; it is to understand that the stream of life, flowing out of the dim past into the uncertain future, is in reality a unified force, though composed of an infinite number and variety of separate lives.
Humanity is a biological species, living in a biological environment, because like all species, we are exquisitely adapted in everything: from our behavior, to our genetics, to our physiology, to that particular environment in which we live. The earth is our home. Unless we preserve the rest of life, as a sacred duty, we will be endangering ourselves by destroying the home in which we evolved, and on which we completely depend.
Quick dinner with ... Ang [Lee] and his wife Jane who's visiting with the children for a while. We talked about her work as a microbiologist and the behaviour of the epithingalingie under the influence of cholesterol. She's fascinated by cholesterol. Says it's very beautiful: bright yellow. She says Ang is wholly uninterested. He has no idea what she does.I check this out for myself. 'What does Jane do?' I ask.'Science,' he says vaguely.
... the reason why we find some things intuitively easy to grasp and others hard, is that our brains are themselves evolved organs: on-board computers, evolved to help us survive in a world (...) where the objects that mattered to our survival were neither very large nor very small; a world where things either stood still or moved slowly compared with the speed of light; and where the very improbable could safely be treated as impossible. Our mental burka window is narrow because it didn't need to be any wider in order to assist our ancestors to survive.
By nature, that mind is easily fooled by supernatural mysticism. It is extremely gullible. And no matter how much we the civilized human beings advance in the fields of modern sciences, there is always a part of us, that tries to allure us with magical nonsense, because that nonsense has been with us since the birth of humanity.
Now you know that the fascinating phenomenon of love has nothing to do with the supernatural entity known as Cupid, but everything to do with neurochemistry. Likewise, divinity is a cerebral creation, not a supernatural one. And it has been long since thinking humanity has learnt that love is a majestic creation of the brain, yet that knowledge hasn’t made love be deemed any less glorious. Then why should it threaten the religious believer to learn that divinity as well is a natural creation of the brain!
It has been long since thinking humanity has learnt that love is a majestic creation of the brain, yet that knowledge hasn’t made love be deemed any less glorious. Then why should it threaten the religious believer to learn that divinity as well is a natural creation of the brain!
Religion is an attempt to get control over the sensory world, in which we are placed, by means of the wish-world, which we have developed inside us as a result of biological and psychological necessities. But it cannot achieve its end. Its doctrines carry with them the stamp of the times in which they originated, the ignorant childhood days of the human race. Its consolations deserve no trust. Experience teaches us that the world is not a nursery. The ethical commands, to which religion seeks to lend its weight, require some other foundations instead, for human society cannot do without them, and it is dangerous to link up obedience to them with religious belief. If one attempts to assign to religion its place in man’s evolution, it seems not so much to be a lasting acquisition, as a parallel to the neurosis which the civilized individual must pass through on his way from childhood to maturity.
In the abstract, it might be tempting to imagine that irreducible complexity simply requires multiple simultaneous mutations - that evolution might be far chancier than we thought, but still possible. Such an appeal to brute luck can never be refuted... Luck is metaphysical speculation; scientific explanations invoke causes.
Among all the occurrences possible in the universe the a priori probability of any particular one of them verges upon zero. Yet the universe exists; particular events must take place in it, the probability of which (before the event) was infinitesimal. At the present time we have no legitimate grounds for either asserting or denying that life got off to but a single start on earth, and that, as a consequence, before it appeared its chances of occurring were next to nil. ... Destiny is written concurrently with the event, not prior to it... The universe was not pregnant with life nor the biosphere with man. Our number came up in the Monte Carlo game. Is it surprising that, like the person who has just made a million at the casino, we should feel strange and a little unreal?
Random mutations much more easily debilitate genes than improve them, and that this is true even of the helpful mutations. Let me emphasize, our experience with malaria’s effects on humans (arguably our most highly studied genetic system) shows that most helpful mutations degrade genes. What’s more, as a group the mutations are incoherent, meaning that they are not adding up to some new system. They are just small changes - mostly degradative - in pre-existing, unrelated genes. The take-home lesson is that this is certainly not the kind of process we would expect to build the astonishingly elegant machinery of the cell. If random mutation plus selective pressure substantially trashes the human genome, why should we think that it would be a constructive force in the long term? There is no reason to think so.
The conclusion of intelligent design flows naturally from the data itself—not from sacred books or sectarian beliefs. Inferring that biochemical systems were designed by an intelligent agent is a humdrum process that requires no new principles of logic or science. It comes simply from the hard work that biochemistry has done over the past forty years, combined with consideration of the way in which we reach conclusions of design every day.
The fundamental claim of intelligent design is straightforward and easily intelligible: namely, there are natural systems that cannot be adequately explained in terms of undirected natural forces and that exhibit features which in any other circumstance we would attribute to intelligence.
Is the conclusion that the universe was designed - and that the design extends deeply into life - science, philosophy, religion, or what? In a sense it hardly matters. By far the most important question is not what category we place it in, but whether a conclusion is true. A true philosophical or religious conclusion is no less true than a true scientific one. Although universities might divide their faculty and courses into academic categories, reality is not obliged to respect such boundaries.
Teaching students the evidence for and against Darwinism is not the same as teaching intelligent design. The U.S. Congress has officially endorsed teaching students 'the full range of scientific views' about Darwinian evolution.
Genetics might be adequate for explaining microevolution, but microevolutionary changes in gene frequency were not seen as able to turn a reptile into a mammal or to convert a fish into an amphibian. Microevolution looks at adaptations that concern the survival of the fittest, not the arrival of the fittest... The origin of species — Darwin’s problem — remains unsolved.
No fossil is buried with its birth certificate. That, and the scarcity of fossils, means that it is effectively impossible to link fossils into chains of cause and effect in any valid way... To take a line of fossils and claim that they represent a lineage is not a scientific hypothesis that can be tested, but an assertion that carries the same validity as a bedtime story—amusing, perhaps even instructive, but not scientific.
The most essential prediction of Darwinism is that, given an astronomical number of chances, unintelligent processes can make seemingly-designed systems, ones of the complexity of those found in the cell. ID specifically denies this, predicting that in the absence of intelligent input no such systems would develop. So Darwinism and ID make clear, opposite predictions of what we should find when we examine genetic results from a stupendous number of organisms that are under relentless pressure from natural selection. The recent genetic results are a stringent test. The results: 1) Darwinism’s prediction is falsified; 2) Design’s prediction is confirmed.
The controversy between Darwinism and intelligent design has the characteristics of major scientific revolutions in the past. Darwinists are losing power because they treat with contempt the very people on whom they depend the most: American taxpayers. The outcome of this scientific revolution will be decided by young people who have the courage to question dogmatism and follow the evidence wherever it leads.
There's no obvious reason to assume that the very same rare properties that allow for our existence would also provide the best overall setting to make discoveries about the world around us. We don't think this is merely coincidental. It cries out for another explanation, an explanation that... points to purpose and intelligent design in the cosmos.
Whenever explaining an event, we must choose from three competing modes of explanation. These are regularity, chance, and design... To attribute an event to design is to say that it cannot reasonably be referred to either regularity or chance.
If Darwinists are opposed to mentioning scientific problems with their view, you would think they would be even more opposed to mentioning intelligent design. Yet Darwinists have been discussing ID in public school science classes for years... Biology textbooks have been mentioning intelligent design since the late 1990s—but only to misrepresent and disparage it.
For those scientists who take it seriously, Darwinian evolution has functioned more as a philosophical belief system than as a testable scientific hypothesis. This quasi-religious function of the theory is, I think, what lies behind many of the extreme statements that you have doubtless encountered from some scientists opposing any critical analysis of neo-Darwinism in the classroom. It is also why many scientists make public statements about the theory that they would not defend privately to other scientists like me.
The phrase 'the fossil record' sounds impressive and authoritative. As used by some persons it becomes, as intended, intimidating, taking on the aura of esoteric truth as expounded by an elite class of specialists. But what is it, really, this fossil record? Only data in search of interpretation. All claims to the contrary that I know, and I know of several, are so much superstition.
Will it be possible to solve these problems? It is certain that nobody has thus far observed the transformation of dead into living matter, and for this reason we cannot form a definite plan for the solution of this problem of transformation. But we see that plants and animals during their growth continually transform dead into living matter, and that the chemical processes in living matter do not differ in principle from those in dead matter. There is, therefore, no reason to predict that abiogenesis is impossible, and I believe that it can only help science if the younger investigators realize that experimental abiogenesis is the goal of biology.
Birth after birth the line unchanging runs,And fathers live transmitted in their sons;Each passing year beholds the unvarying kinds,The same their manners, and the same their minds:Till, as erelong successive buds decay,And insect-shoals successive pass away,Increasing wants the pregnant parent vexWith the fond wish to form a softer sex. ..
The complexity of the simplest known type of cell is so great that it is impossible to accept that such an object could have been thrown together suddenly by some kind of freakish, vastly improbable, event. Such an occurrence would be indistinguishable from a miracle.
The very comprehensibility of the world points to an intelligence behind the world. Indeed, science would be impossible if our intelligence were not adapted to the intelligibility of the world. The match between our intelligence and the intelligibility of the world is no accident. Nor can it properly be attributed to natural selection, which places a premium on survival and reproduction and has no stake in truth or conscious thought. Indeed, meat-puppet robots are just fine as the output of a Darwinian evolutionary process.
Molecular biology has shown that even the simplest of all living systems on the earth today, bacterial cells, are exceedingly complex objects. Although the tiniest bacterial cells are incredibly small, weighing less than 10-12 gms, each is in effect a veritable micro-miniaturized factory containing thousands of exquisitely designed pieces of intricate molecular machinery, made up altogether of one hundred thousand million atoms, far more complicated than any machine built by man and absolutely without parallel in the nonliving world.
To grasp the reality of life as it has been revealed by molecular biology, we must magnify a cell a thousand million times until it is twenty kilometers in diameter and resembles a giant airship large enough to cover a great city like London or New York. What we would then see would be an object of unparalleled complexity and adaptive design. On the surface of the cell we would see millions of openings, like the port holes of a vast space ship, opening and closing to allow a continual stream of materials to flow in and out. If we were to enter one of these openings we would find ourselves in a world of supreme technology and bewildering complexity.
To establish evolutionary interrelatedness invariably requires exhibiting similarities between organisms. Within Darwinism, there's only one way to connect such similarities, and that's through descent with modification driven by the Darwinian mechanism. But within a design-theoretic framework, this possibility, though not precluded, is also not the only game in town. It's possible for descent with modification instead to be driven by telic processes inherent in nature (and thus by a form of design). Alternatively, it's possible that the similarities are not due to descent at all but result from a similarity of conception, just as designed objects like your TV, radio, and computer share common components because designers frequently recycle ideas and parts. Teasing apart the effects of intelligent and natural causation is one of the key questions confronting a design-theoretic research program. Unlike Darwinism, therefore, intelligent design has no immediate and easy answer to the question of common descent.Darwinists necessarily see this as a bad thing and as a regression to ignorance. From the design theorists' perspective, however, frank admissions of ignorance are much to be preferred to overconfident claims to knowledge that in the end cannot be adequately justified. Despite advertisements to the contrary, science is not a juggernaut that relentlessly pushes back the frontiers of knowledge. Rather, science is an interconnected web of theoretical and factual claims about the world that are constantly being revised and for which changes in one portion of the web can induce radical changes in another. In particular, science regularly confronts the problem of having to retract claims that it once confidently asserted.
The information contained in an English sentence or computer software does not derive from the chemistry of the ink or the physics of magnetism, but from a source extrinsic to physics and chemistry altogether. Indeed, in both cases, the message transcends the properties of the medium. The information in DNA also transcends the properties of its material medium.
Real arms races are run by highly intelligent, bespectacled engineers in glass offices thoughtfully designing shiny weapons on modern computers. But there's no thinking in the mud and cold of nature's trenches. At best, weapons thrown together amidst the explosions and confusion of smoky battlefields are tiny variations on old ones, held together by chewing gum. If they don't work, then something else is thrown at the enemy, including the kitchen sink - there's nothing "progressive" about that. At its usual worst, trench warfare is fought by attrition. If the enemy can be stopped or slowed by burning your own bridges and bombing your own radio towers and oil refineries, then away they go. Darwinian trench warfare does not lead to progress - it leads back to the Stone Age.
Before you can ask 'Is Darwinian theory correct or not?', You have to ask the preliminary question 'Is it clear enough so that it could be correct?'. That's a very different question. One of my prevailing doctrines about Darwinian theory is 'Man, that thing is just a mess. It's like looking into a room full of smoke.' Nothing in the theory is precisely, clearly, carefully defined or delineated. It lacks all of the rigor one expects from mathematical physics, and mathematical physics lacks all the rigor one expects from mathematics. So we're talking about a gradual descent down the level of intelligibility until we reach evolutionary biology.
Even if we have a reliable criterion for detecting design, and even if that criterion tells us that biological systems are designed, it seems that determining a biological system to be designed is akin to shrugging our shoulders and saying God did it. The fear is that admitting design as an explanation will stifle scientific inquiry, that scientists will stop investigating difficult problems because they have a sufficient explanation al
The secret of DNA's success is that it carries information like that of a computer program, but far more advanced. Since experience shows that intelligence is the only presently acting cause of information, we can infer that intelligence is the best explanation for the information in DNA.
Things that look like they were designed, probably were... If intelligence is an operative component of the universe, a science that methodologically excludes its existence will be susceptible to being trapped in an endless chase for materialistic causes that do not exist... Where there are sufficient grounds for inferring intelligent causation, based on evidence of "specified complexity," it should be considered as a component of scientific theories.Inclusion of intelligent causation in the scientific equation is not novel and has not impeded the practice of science in the past, e.g. Newton and Kepler, in an age when science was not constrained by a philosophical materialism, and by many current scientists who have remained open to following the evidence where it leads.
Constrained optimization is the art of compromise between conflicting objectives. This is what design is all about. To find fault with biological design - as Stephen Jay Gould regularly does - because it misses some idealized optimum is therefore gratuitous. Not knowing the objectives of the designer, Gould is in no position to say whether the designer has proposed a faulty compromise among those objectives.
Throughout 150 years of the science of bacteriology, there is no evidence that one species of bacteria has changed into another... Since there is no evidence for species changes between the simplest forms of unicellular life, it is not surprising that there is no evidence for evolution from prokaryotic [i.e., bacterial] to eukaryotic [i.e., plant and animal] cells, let alone throughout the whole array of higher multicellular organisms.
Even if the intelligent design of some structure has been established, it still is a separate question whether a wise, powerful, and beneficent God ought to have designed a complex, information-rich structure one way or another. For the sake of argument, let's grant that certain designed structures are not simply, as Gould put it, "odd" or "funny," but even cruel. What of it? Philosophical theology has abundant resources for dealing with the problem of evil, maintaining a God who is both omnipotent and benevolent in the face of evil.
I recently asked more than seventy eminent researchers if they would have done I their work differently if they had thought Darwin's theory was wrong. The responses were all the same: no. I also examined the outstanding biodiscoveries of the past century: the discovery of the double helix; the characterization of the ribosome: the mapping of genomes; research on medications and drug reactions: improvements in food production and sanitation; the development of new surgeries; and others. I even queried biologists working in areas where one would expect the Darwinian paradigm to have most benefited research, such as the emergence of resistance to antibiotics and pesticides. Here, as elsewhere, I found that Darwin's theory had provided no discernible guidance, but was brought in, after the breakthroughs, as an interesting narrative gloss.
I am absolutely convinced of the lack of true scientific evidence in favour of Darwinian dogma. Nobody in the biological sciences, medicine included, needs Darwinism at all. Darwinism is certainly needed, however, in order to pose as a philosopher, since it is primarily a worldview. And an awful one, as George Bernard Shaw used to say.
Molecular machines display a key signature or hallmark of design, namely, irreducible complexity. In all irreducibly complex systems in which the cause of the system is known by experience or observation, intelligent design or engineering played a role in the origin of the system... We find such systems within living organisms.
All disciplines of science are built on the causality of the relationships governing related events. Yet the theory of evolution is built upon the idea of accidental changes that resulted in complex living systems. I was unable to comprehend how the notion that an infinite number of random accidents systematically happened to produce living species, and kept improving these beings, is justified.
From year to year, and from age to age, we see [biologists] at work, adding no doubt much to the unknown, and advancing many important interests, but, at the same time, doing little for the establishment of comprehensive views of nature. Experiments in however narrow a walk, facts of whatever minuteness, make reputations in scientific societies; all beyond is regarded with suspicion and distrust.
Scientists rightly resist invoking the supernatural in scientific explanations for fear of committing a god-of-the-gaps fallacy (the fallacy of using God as a stop-gap for ignorance). Yet without some restriction on the use of chance, scientists are in danger of committing a logically equivalent fallacy-one we may call the “chance-of-the-gaps fallacy.” Chance, like God, can become a stop-gap for ignorance.
Teachers seeking to 'teach the controversy' over Darwinian evolution in today's climate will likely be met with false warnings that it is unconstitutional to say anything negative about Darwinian evolution. Students who attempt to raise questions about Darwinism, or who try to elicit from the teacher an honest answer about the status of intelligent design theory will trigger administrators' concerns about whether they stand in Constitutional jeopardy. A chilling effect on open inquiry is being felt in several states already, including Ohio. South Carolina, and Pennsylvania. [District Court] Judge Jones's message is clear: give Darwin only praise, or else face the wrath of the judiciary.
That enormously complex biological interactions are so flawlessly coordinated as to result in such obvious manifestations as human thought or the electrical activity that dries the heartbeat is as exciting to me -- actually more exciting -- than such phenomena were when I was a small boy and thought them divinely (in the supernatural sense) driven.
Was intelligence an inevitability, a consequence of evolution? Bacteria succeeded without a brain, possessing survival skills that rivaled their biological hosts. So why should a creature of higher intelligence expect to do better? Humans were on the verge of being replaced by their hybrid creations. How intelligent was that?
Stopping in the 1970s, "Hybridity" as the fifth and final chapter is less of an end point than a certain realization of the artifice, plasticity, and technology that Wells and Loeb envisioned as the future of the human relationship to living matter as well as of the "catastrophic" situation that Georges Canghuilhem (following Kurt Goldstein) saw in life subjected to the milieu of the laboratory.
Biochemists assume that the three cellular kingdoms evolved from a single common ancestor, because the alternative of supposing an independent origin of life two or more times presents still greater difficulties. The common ancestor is merely hypothetical, as are the numerous transitional intermediate forms that would have to connect such enormously different groups to the ancestor. From a Darwinist viewpoint all these hypothetical creatures are a logical necessity, but there is no empirical confirmation that they existed.
I approach the creation-evolution dispute not as a scientist but as a problem of law, which means among other things that I know something about the ways that words are used in arguments. What first drew my attention to the question was the way the rules of argument seemed to be structured to make it impossible to question whether what we are being told about evolution is really true. For example, the Academy's rule against negative argument automatically eliminates the possibility that science has not discovered how complex organisms could have developed. However wrong the current answer may be, it stands until a better answer arrives. It is as if a criminal defendant were not allowed to present an alibi unless he could also show who did commit the crime.
There is no definitive answer as to why cannibalism provides us with such stimulation, although what is clear, and what remains extremely disturbing for me, is our increasing desensitization to violence and gore - a trait that does not bode well for the future.
Ever since the field of biology emerged in the United States and Europe at the start of the nineteenth century, it has been bound up in debates over sexual, racial, and national politics. And as our social viewpoints have shifted, so has the science of the body.
Another explanation for the failure of logic and observation alone to advance medicine is that unlike, say, physics, which uses a form of logic - mathematics - as its natural language, biology does not lend itself to logic. Leo Szilard, a prominent physicist, made this point when he complained that after switching from physics to biology he never had a peaceful bath again. As a physicist he would soak in the warmth of a bathtub and contemplate a problem, turn it in his mind, reason his way through it. But once he became a biologist, he constantly had to climb out of the bathtub to look up a fact.
In fact, biology is chaos. Biological systems are the product not of logic but of evolution, an inelegant process. Life does not choose the logically best design to meet a new situation. It adapts what already exists...The result, unlike the clean straight lines of logic, is often irregular, messy.
Sorgan tried his very best not to think about how long it must have taken for a stream that small to eat its way down through solid rock to form its current bed. Sorgan knew exactly what the word “hundred” meant, but when numbers wandered off toward “thousand”—or even “million”—and the people who used those terms were talking about years, Sorgan’s mind shied back in horror.
Inside a jihadi brain, the neuropsychological elements of aggression and rage run rampant, due to socio-political conditions. These overwhelming mental elements of young souls, when attached to the sacred texts of the Quran, by the authoritarian groups of fundamentalists, become weapons of mass destruction in the pursuit of the exclusive supremacy of one religion over the others.
All the so-called philosophical notion of “love without attachment” or “detached love” are biologically non-existent on this planet. We humans are biologically designed through millions of years of evolution to grow attachment. Love cannot survive without attachment.
I wanted to present Neuroscience to people in a way that would diminish their differences.
Neuroscience makes us connect with each other at an emotional level. It makes us make friends. It makes us dream more positively. It makes us more optimistic about ourselves and the world even in our darkest days. It makes us achieve our goal endowed with strength even through immense miseries. It allows us to attain the subjective reality of our fellow humans. Imbued with the understanding of the mind we can walk in the shoes of other people.
Few pretty and privileged young women really understand the essential injustice of biology...For most of her life as a woman, the rules were perfectly clear cut: other women were the enemy, and all love was war. She had rejected feminism, quite openly, as a crutch for the envious and ugly, and regarded married women as holding the upper hand if, unlike her own mother, they had any strength of character. The weaknesses and dependencies imposed by fecundity had never entered into her calculations.
Marian’s eyes absolutely blaze. To meet them is to have a shock of contact as if they were electrically charged. “Now you see? You wondered what was in whale’s milk. Don’t you know now? The same thing that’s in a mushroom spore so small you need a microscope to see it, or in gophers, or poison oak, or anything else we try to pave under or grub out, or poison. There isn’t good life and bad life, there’s only life. Think of the force down there, just telling things to get born!
This had not endeared him to exobiologists such as Dr Perera, who took exactly the opposite view. To them, the only purpose of the Universe was the production of intelligence, and they were apt to talk sneeringly about purely astronomical phenomena, 'Mere dead matter' was one of their favourite phrases.
If we wish to know about a man, we ask 'what is his story--his real, inmost story?'--for each of us is a biography, a story. Each of us is a singular narrative, which is constructed, continually, unconsciously, by, through, and in us--through our perceptions, our feelings, our thoughts, our actions; and, not least, our discourse, our spoken narrations. Biologically, physiologically, we are not so different from each other; historically, as narratives--we are each of us unique.
We biologists often use the phrase “Mother Nature” to refer to the entire system of Nature that we see around us, but it is not really an entity, and it does not have any real concern for any of its living creatures – it lives on with or without us; it is in our human psychology to impose a human-like identity upon any grand system that we encounter around us – it gives us a sense of closeness to that system and makes us feel an essential part of it. When I say, Mother Nature designed us, or programmed us, I am simply referring to the process of natural selection.
When Mother Nature speaks, even the Gods hold silence.
Trees live in symbiosis with hyphae (fungus/mold roots). A tea spoon of dirt contains kilometers of these roots. One species can spread throughout entire forests over centuries. They exchange nutrients with trees, along with information about insects, drought and other dangers. It's like a 'wood wide web'.
In biology, nothing is clear, everything is too complicated, everything is a mess, and just when you think you understand something, you peel off a layer and find deeper complications beneath. Nature is anything but simple.
The race is now on between the technoscientific and scientific forces that are destroying the living environment and those that can be harnessed to save it. . . . If the race is won, humanity can emerge in far better condition than when it entered, and with most of the diversity of life still intact.
Our present intricate humanly consciousness evolved after a long journey of struggle. And the beauty of natural selection is that our struggle against nature made us worthy of being rewarded with the 3 lbs. lump of highly advanced biological computer by our Mother Nature herself.
In AP Bio, I learned that the cells in our body are replaced every seven years, which means that one day I'll have a body full of cells that were never sick. But it also means that the parts of me that knew and loved Sadie will disappear. I'll still remember loving her, but it'll be a different me who loved her. And maybe this is how we move on. We grow new cells to replace the grieving ones, diluting our pain until it loses potency.
The externalization of memory [via the use of external symbolic storage systems] has altered the actual memory architecture within which humans think, which is changing the role of biological memory, the way in which the human brain deploys its resources, and the form of modern culture.
Oh I believe in loving cats and dogs and children and parents – sometimes – but I don’t believe in romantic love. Of course, there’s the momentary rush of hormones and chemicals that encourages us to mate, but it’s biology – it’s no more inherently mystical than the nicotine in that cigarette you’re smoking
When I am fully immersed in my work of nourishing humanity, it fills my head with all kinds of feel-good chemicals, such as endorphins, serotonin and dopamine. Problems occur during the brief intervals between the finishing of one work and the beginning of another. During these intervals, my biology starts to get filled with stress hormones cortisol and adrenalin, that worsens my OCD. That is why, I can’t sit still even a day after I finish writing a book. Because if I do, my OCD begins to suffocate me inside my head. Hence, as soon as I deliver a work, I have to start working on my next scientific literature.
Biomasses are a biological reality that cannot be denied as existing, but even though they exist physically, yet they have not attained the height of Homo sapiens. Humans could be termed as biomasses when they don’t fully put into use their human qualifications. Men and women that don’t bother to think. Men and women that don’t bother to notice things that are out of order. People who are indifferent about the happenings around them. Men and women that don’t respond with solution to the challenges of the era. All of these people are united by one common name BIOMASSES.
The more formidable the contradiction between inexhaustible life-joy and inevitable fate, the greater the longing which reveals itself in the kingdom of poetry and in the self-created world of dreams hopes to banish the dark power of reality. The gods enjoy eternal youth, and the search for the means of securing it was one of the occupations of the heroes of mythology and the sages, as it was of real adventurers in the middle ages and more recent times. . . . But the fountain of youth has not been found, and can not be found if it is sought in any particular spot on the earth. Yet it is no fable, no dream-picture; it requires no adept to find it: it streams forth inexhaustible in all living nature.
Men write more books. Men give more lectures. Men ask more questions after lectures. Men post more e-mail to Internet discussion groups. To say this is due to patriarchy is to beg the question of the behavior's origin. If men control society, why don't they just shut up and enjoy their supposed prerogatives? The answer is obvious when you consider sexual competition: men can't be quiet because that would give other men a chance to show off verbally. Men often bully women into silence, but this is usually to make room for their own verbal display. If men were dominating public language just to maintain patriarchy, that would qualify as a puzzling example of evolutionary altruism—a costly, risky individual act that helps all of one's sexual competitors (other males) as much as oneself. The ocean of male language that confronts modern women in bookstores, television, newspapers, classrooms, parliaments, and businesses does not necessarily come from a male conspiracy to deny women their voice. It may come from an evolutionary history of sexual selection in which the male motivation to talk was vital to their reproduction.
In order to approximate those shapes and attitudes which are considered normal and desirable, both sexes deform themselves, justifying the process by referring to the primary, genetic difference between the sexes. But of forty-eight chromosomes only one is different: on this difference we base a complete separation of male and female, pretending as it were that all forty-eight were different.
...because the great beauty of embryo development, the bit that human beings find so hard to grasp, is that it is a totally decentralised process...no cell need wait for instructions from authority; every cell can act on its own information and the signals it receives from its neighbours. We do not organise societies that way...Perhaps we should try.
Throughout history we humans have struggled to find meaning in the awesome contradiction of our human condition. Neither philosophy, nor psychology nor biology has, until now, been able to provide the truthful explanation.
It is difficult to overstate the importance of understanding mirror neurons and their function. They may well be central to social learning, imitation, and the cultural transmission of skills and attitudes—perhaps even of the pressed-together sound clusters we call words. By hyperdeveloping the mirror-neuron system, evolution in effect turned culture into the new genome. Armed with culture, humans could adapt to hostile new environments and figure out how to exploit formerly inaccessible or poisonous food sources in just one or two generations—instead of the hundreds or thousands of generations such adaptations would have taken to accomplish through genetic evolution.Thus culture became a significant new source of evolutionary pressure, which helped select brains that had even better mirror-neuron systems and the imitative learning associated with them. The result was one of the many self-amplifying snowball effects that culminated in Homo sapiens, the ape that looked into its own mind and saw the whole cosmos reflected inside.
The offspring cannot rely on its parents for disinterested guidance. One expects the offspring to be preprogrammed to resist some parental manipulation while being open to other forms. When the parent imposes an arbitrary system of reinforcement (punishment and reward) in order to manipulate the offspring to act against its own best interests, selection will favor offspring that resist such schedules of reinforcement.
If, again, the most superficial introspection teaches the physiologist that his conscious life is dependent upon the mechanical adjustments of his body, and that inversely his body is subjected with certain limitations to his will, then it only remains for him to make one assumption more, namely, that this mutual interdependence between the spiritual and the material is itself also dependent on law, and he has discovered the bond by which the science of the matter and the science of consciousness are united into a single whole.
The emotional mind likewise transcends the facile and appealing dualism separating its psychological and biological aspects. Physical mechanisms produce one’s experience of the world. Experience, in turn, remodels the neurons whose chemoelectric messages create consciousness. Selecting one strand of that eternal braid and assigning it primacy is the height of capriciousness. (168)
In the distant future I see open fields for far more important researches. Psychology will be based on a new foundation, that of the necessary acquirement of each mental power and capacity by gradation. Light will be thrown on the origin of man and his history.
Wherever sufficiently numerous series of the remains of any given group, which has endured for a long space of time, are carefully examined, their morphological relations are never in discordance with the requirements of the doctrine of evolution, and often afford convincing evidence of it. At the same time, it has been shown that certain forms persist with very little change, from the oldest to the newest fossiliferous formations; and thus show that progressive development is a contingent, and not a necessary result, of the nature of living matter.
Nature has but one plan of operation, invariably the same in the smallest things as well as in the largest, and so often do we see the smallest masses selected for use in Nature, that even enormous ones are built up solely by fitting these together. Indeed, all Nature's efforts are devoted to uniting the smallest parts of our bodies in such a way that all things whatsoever, however diverse they may be, which coalesce in the structure of living things construct the parts by means of a sort of compendium.
[On scientist Carl Friedrich Gauss][Carl Friedrich] Gauss told his friend Rudolf Wagner, a professor of biology at Gottingen University, that he did not believe in the Bible but that he had meditated a great deal on the future of the human soul and speculated on the possibility of the soul being reincarnated on another planet. Evidently, Gauss was a Deist with a good deal of skepticism concerning religion.
All the more recent work on alkaptonuria has... strengthened the belief that the homogentisic acid excreted is derived from tyrosine, but why alkaptonuric individuals pass the benzene ring of their tyrosine unbroken and how and where the peculiar chemical change from tyrosine to homogentisic acid is brought about, remain unsolved problems.
The curious fact is that biology tells us nothing about desire. And, when you think about it, culture -- novels, movies, opera, and quite a lot of painting -- is about desire, how we manage desire, how we suffer from it, and how it brings us joy when we get things right. A story without desire -- and that means without the insistence of desire -- will be empty, dry, and more or less aimless. That is one reason we read novels, to see how people fall into awkward moral situations and then try to extricate themselves. This is why there is so much anguish in the world: frustrated desire is every bit as miserable as poverty, because desire is no respecter of one’s position in life: everyone goes through it.
Every hour of your life that ticks by, there are numerous points and moments when you can choose to pause - and be aware of your mental and physical state. At any given point, you can freeze the flow that is your life, and be fully conscious for a moment.
That all plants immediately and substantially stem from the element water alone I have learnt from the following experiment. I took an earthern vessel in which I placed two hundred pounds of earth dried in an oven, and watered with rain water. I planted in it a willow tree weighing five pounds. Five years later it had developed a tree weighing one hundred and sixty-nine pounds and about three ounces. Nothing but rain (or distilled water) had been added. The large vessel was placed in earth and covered by an iron lid with a tin-surface that was pierced with many holes. I have not weighed the leaves that came off in the four autumn seasons. Finally I dried the earth in the vessel again and found the same two hundred pounds of it diminished by about two ounces. Hence one hundred and sixty-four pounds of wood, bark and roots had come up from water alone.
... on these expanded membranes [butterfly wings] Nature writes, as on a tablet, the story of the modifications of species, so truly do all changes of the organisation register themselves thereon. Moreover, the same colour-patterns of the wings generally show, with great regularity, the degrees of blood-relationship of the species. As the laws of nature must be the same for all beings, the conclusions furnished by this group of insects must be applicable to the whole world.
She had a theory that the fear of getting in trouble was what made her not as good a programmer and that, in fact, it was all linked to testosterone, and that was why there were more guy programmers than women. It was a very hazy theory, and she didn't like it, but she had pretty much convinced herself it was true, although she couldn't bear to think of sharing it with anybody, because it was a lot better to think that there were social reasons why girls didn't usually become code monkeys than to think there were biological reasons.
The evolutionists, piercing beneath the show of momentary stability, discovered, hidden in rudimentary organs, the discarded rubbish of the past. They detected the reptile under the lifted feathers of the bird, the lost terrestrial limbs dwindling beneath the blubber of the giant cetaceans. They saw life rushing outward from an unknown center, just as today the astronomer senses the galaxies fleeing into the infinity of darkness. As the spinning galactic clouds hurl stars and worlds across the night, so life, equally impelled by the centrifugal powers lurking in the germ cell, scatters the splintered radiance of consciousness and sends it prowling and contending through the thickets of the world.
Not only in antiquity but in our own times also laws have been passed...to secure good conditions for workers; so it is right that the art of medicine should contribute its portion for the benefit and relief of those for whom the law has shown such foresight...[We] ought to show peculiar zeal...in taking precautions for their safety. I for one have done all that lay in my power, and have not thought it beneath me to step into workshops of the meaner sort now and again and study the obscure operations of mechanical arts.
In Galapagos, as elsewhere, things of the mind, including intellectual ramifications from evolutionary theory, and things of the spirit, like the feeling one gets from a Queen Anne’s lace of stars in the moonless Galapagean sky, struggle toward accommodation with an elementary desire for material comfort…because so many regard this archipelago as preeminently a terrain of the mind and spirit, a locus of biological thought and psychological rejuvenation. The sheer strength of Darwin’s insight into the development of biological life gently urges a visitor to be more than usually observant here- to notice, say, that while the thirteen Galapagean finches are all roughly the same hue, it is possible to separate them according to marked differences in the shapes of their bills and feeding habits.
There is a time and place for electromagnetic shielding and I regard it as a last resort due to the long term biological problems that I have observed with it over the years in plant growth experiments.
My own experience of over 60 years in biomedical research amply demonstrated that without the use of animals and of human beings, it would have been impossible to acquire the important knowledge needed to prevent much suffering and premature death not only among humans but also among [other] animals.
Healing is a biological process, not an art. It is as much a function of the living organism as respiration, digestion, circulation, excretion, cell proliferation, or nerve activity. It is a ceaseless process, as constant as the turning of the earth on its axis. Man can neither duplicate nor imitate nor provide a substitute for the process. All schools of healing are frauds.
Suddenly I realized that a cell's life is controlled by the physical and energetic environment and not by its genes. Genes are simply molecular blueprints used in the construction of cells, tissues, and organs. The environment serves as a "contractor" who reads and engages those genetic blueprints and is ultimately responsible for the character of a cell's life. It is a single cell's "awareness" of the environment, not its genes, that sets into motion the mechanisms of life.
When General Genius built the first mentar [Artificial Intelligence] mind in the last half of the twenty-first century, it based its design on the only proven conscious material then known, namely, our brains. Specifically, the complex structure of our synaptic network. Scientists substituted an electrochemical substrate for our slower, messier biological one. Our brains are an evolutionary hodgepodge of newer structures built on top of more ancient ones, a jury-rigged system that has gotten us this far, despite its inefficiency, but was crying out for a top-to-bottom overhaul.Or so the General genius engineers presumed. One of their chief goals was to make minds as portable as possible, to be easily transferred, stored, and active in multiple media: electronic, chemical, photonic, you name it. Thus there didn't seem to be a need for a mentar body, only for interchangeable containers. They designed the mentar mind to be as fungible as a bank transfer.And so they eliminated our most ancient brain structures for regulating metabolic functions, and they adapted our sensory/motor networks to the control of peripherals.As it turns out, intelligence is not limited to neural networks, Merrill. Indeed, half of human intelligence resides in our bodies outside our skulls. This was intelligence the mentars never inherited from us....The genius of the irrational......We gave them only rational functions -- the ability to think and feel, but no irrational functions... Have you ever been in a tight situation where you relied on your 'gut instinct'? This is the body's intelligence, not the mind's. Every living cell possesses it. The mentar substrate has no indomitable will to survive, but ours does.Likewise, mentars have no 'fire in the belly,' but we do. They don't experience pure avarice or greed or pride. They're not very curious, or playful, or proud. They lack a sense of wonder and spirit of adventure. They have little initiative. Granted, their cognition is miraculous, but their personalities are rather pedantic.But probably their chief shortcoming is the lack of intuition. Of all the irrational faculties, intuition in the most powerful. Some say intuition transcends space-time. Have you ever heard of a mentar having a lucky hunch? They can bring incredible amounts of cognitive and computational power to bear on a seemingly intractable problem, only to see a dumb human with a lucky hunch walk away with the prize every time. Then there's luck itself. Some people have it, most don't, and no mentar does.So this makes them want our bodies...Our bodies, ape bodies, dog bodies, jellyfish bodies. They've tried them all. Every cell knows some neat tricks or survival, but the problem with cellular knowledge is that it's not at all fungible; nor are our memories. We're pretty much trapped in our containers.
Darwin, with his Origin of Species, his theories about Natural Selection, the Survival of the Fittest, and the influence of environment, shed a flood of light upon the great problems of plant and animal life.These things had been guessed, prophesied, asserted, hinted by many others, but Darwin, with infinite patience, with perfect care and candor, found the facts, fulfilled the prophecies, and demonstrated the truth of the guesses, hints and assertions. He was, in my judgment, the keenest observer, the best judge of the meaning and value of a fact, the greatest Naturalist the world has produced.The theological view began to look small and mean.Spencer gave his theory of evolution and sustained it by countless facts. He stood at a great height, and with the eyes of a philosopher, a profound thinker, surveyed the world. He has influenced the thought of the wisest.Theology looked more absurd than ever.Huxley entered the lists for Darwin. No man ever had a sharper sword -- a better shield. He challenged the world. The great theologians and the small scientists -- those who had more courage than sense, accepted the challenge. Their poor bodies were carried away by their friends.Huxley had intelligence, industry, genius, and the courage to express his thought. He was absolutely loyal to what he thought was truth. Without prejudice and without fear, he followed the footsteps of life from the lowest to the highest forms.Theology looked smaller still.Haeckel began at the simplest cell, went from change to change -- from form to form -- followed the line of development, the path of life, until he reached the human race. It was all natural. There had been no interference from without.I read the works of these great men -- of many others – and became convinced that they were right, and that all the theologians -- all the believers in "special creation" were absolutely wrong.The Garden of Eden faded away, Adam and Eve fell back to dust, the snake crawled into the grass, and Jehovah became a miserable myth.
We need science education to produce scientists, but we need it equally to create literacy in the public. Man has a fundamental urge to comprehend the world about him, and science gives today the only world picture which we can consider as valid. It gives an understanding of the inside of the atom and of the whole universe, or the peculiar properties of the chemical substances and of the manner in which genes duplicate in biology. An educated layman can, of course, not contribute to science, but can enjoy and participate in many scientific discoveries which as constantly made. Such participation was quite common in the 19th century, but has unhappily declined. Literacy in science will enrich a person's life.
If a single cell, under appropriate conditions, becomes a man in the space of a few years, there can surely be no difficulty in understanding how, under appropriate conditions, a cell may, in the course of untold millions of years, give origin to the human race.
Fleshers used to spin fantasies about aliens arriving to ‘conquer’ Earth, to steal their ‘precious’ physical resources, to wipe them out for fear of ‘competition’…as if a species capable of making the journey wouldn’t have had the power, or the wit, or the imagination, to rid itself of obsolete biological imperatives. Conquering the Galaxy is what bacteria with spaceships would do – knowing no better, having no choice.
The difference between bush and ladder also allows us to put a lid on a fruitless and boring debate. That debate is over what qualifies as True Language. One side lists some qualities that human language has but that no animal has yet demonstrated: reference, use of symbols displaced of in time and space from their referents, creativity, categorical speech perception, consistent ordering, hierarchical structure, infinity, recursion, and so on. The other side finds some counter-example in the animal kingdom (perhaps budgies can discriminate speech sounds, or dolphins or parrots can attend to word order when carrying out commands, or some songbird can improvise indefinitely without repeating itself), and gloats that the citadel of human uniqueness has been breached. The Human Uniqueness team relinquishes that criterion but emphasizes others or adds new ones to the list, provoking angry objections that they are moving the goalposts. To see how silly this all is, imagine a debate over whether flatworms have True Vision or houseflies have True Hands. Is an iris critical? Eyelashes? Fingernails? Who cares? This is a debate for dictionary-writers, not scientists. Plato and Diogenes were not doing biology when Plato defined man as a "featherless biped" and Diogenes refuted him with a plucked chicken.
...on opening the incubator I experienced one of those rare moments of intense emotion which reward the research worker for all his pains: at first glance I saw that the broth culture, which the night before had been very turbid was perfectly clear: all the bacteria had vanished... as for my agar spread it was devoid of all growth and what caused my emotion was that in a flash I understood: what causes my spots was in fact an invisible microbe, a filterable virus, but a virus parasitic on bacteria. Another thought came to me also, If this is true, the same thing will have probably occurred in the sick man. In his intestine, as in my test-tube, the dysentery bacilli will have dissolved away under the action of their parasite. He should now be cured.
In real life there is no such person as the average man. There are only particular men, women and children, each with his or her inborn idiosyncrasies of mind and body, and all trying (or becoming compelled) to squeeze their biological diversities into the uniformity of some cultural mold.
How can we distinguish what is biologically determined from what people merely try to justify through biological myths? A good rule of thumb is ‘Biology enables, Culture forbids.’ Biology is willing to tolerate a very wide spectrum of possibilities. It’s culture that obliges people to realize some possibilities while forbidding others. Biology enables women to have children – some cultures oblige women to realize this possibility. Biology enables men to enjoy sex with one another – some cultures forbid them to realize this possibility. Culture tends to argue that it forbids only that which is unnatural. But from a biological perspective, nothing is unnatural. Whatever is possible is by definition also natural. A truly unnatural behavior, one that goes against the laws of nature, simply cannot exist.
Perhaps if zoologists would contemplate the wide variations presented by many plants of indubitably one and the same species, and the still wider diversities of long cultivated races from an original stock, they would find more than one instructive parallel to the case of the longest domesticated of all species, man.
In AP Bio, I learned that the cells in our body are replaced every seven years, which means that one day, I'll have a body full of cells that were never sick. But it also means that parts of me that knew and loved Sadie will disappear. I'll still remember loving her, but it'll be a different me who loved her. And maybe this is how we move on. We grow new cells to replace the grieving ones, diluting our pain until it loses potency.The percentage of my skin that touched hers will lessen until one day my lips won't be the same lips that kissed hers, and all I'll have are the memories. Memories of cottages in the woods, arranged in a half-moon. Of the tall metal tray return in the dining hall. Of the study tables in the library. The rock where we kissed. The sunken boat in Latham's lake, Sadie, snapping a photograph, laughing the lunch line, lying next to me at the movie night in her green dress, her voice on the phone, her apple-flavored lips on mine. And it's so unfair. All of it.
One of my friends compared me to Bruce Banner, due to my work with radiation and human health. So I looked up Bruce Banner and this is what I found: Banner, a physicist, is sarcastic and seemingly very self-assured when he first appears in Incredible Hulk #1, but is also emotionally withdrawn in most fashions...Banner is considered one of the greatest scientific minds on Earth, possessing "a mind so brilliant it cannot be measured on any known intelligence test." He holds expertise in biology, chemistry, engineering, physiology, and nuclear physics.
It is, however, a most astonishing but incontestable fact, that the history of the evolution of man as yet constitutes no part of general education. Indeed, our so-called 'educated classes' are to this day in total ignorance of the most important circumstances and the most remarkable phenomena which Anthropogeny has brought to light.
Originally, the atoms of carbon from which we’re made were floating in the air, part of a carbon dioxide molecule. The only way to recruit these carbon atoms for the molecules necessary to support life—the carbohydrates, amino acids, proteins, and lipids—is by means of photosynthesis. Using sunlight as a catalyst the green cells of plants combine carbon atoms taken from the air with water and elements drawn from the soil to form the simple organic compounds that stand at the base of every food chain. It is more than a figure of speech to say that plants create life out of thin air.
Advocacy of leaf protein as a human food is based on the undisputed fact that forage crops (such as lucerne) give a greater yield of protein than other types of crops. Even with conventional food crops there is more protein in the leafy parts than in the seeds or tubs that are usually harvested.
For who could better describe the eye than God, Who made it? But as it is clearer than the day that God has left a good deal to our own efforts ... we should really follow in these things the thread of nature, by which first principles, reason and daily experience lead us. Therefore, He prompts the minds of great men to inquire into the nature which He created, and He furthers and conducts their studies. These things must be enough to us, and from Holy Scripture we should seek in the first place only those things which are necessary to salvation.
All interpretation or observation of reality is necessarily fiction. In this case, the problem is that man is a moral animal abandoned in an amoral universe and condemned to a finite existence with no other purpose than to perpetuate the natural cycle of the species. It is impossible to survive in a prolonged state of reality, at least for a human being. We spend a good part of our lives dreaming, especially when we're awake. As I said, pure biology.
My practice as a scientist is atheistic. That is to say, when I set up an experiment I assume that no god, angel or devil is going to interfere with its course; and this assumption has been justified by such success as I have achieved in my professional career. I should therefore be intellectually dishonest if I were not also atheistic in the affairs of the world.
Who gave the decisive deathblow to the argument from design on the basis of biological complexity? Both philosophers and biologists are divided on this point (Oppy 1996; Dawkins 1986; Sober 2008). Some have claimed that the biological design argument did not falter until Darwin provided a proper naturalistic explanation for adaptive complexity; others maintain that David Hume had already shattered the argument to pieces by sheer logical force several decades earlier, in his Dialogues Concerning Natural Religion (Hume 2007 [1779]). Elliott Sober has been among the philosophers who maintain that, as Hume was not in a position to offer a serious alternative explanation of adaptive complexity, it is hardly surprising that 'intelligent people strongly favored the design hypothesis' (Sober 2000, 36). In his most recent book, however, Sober (2008) carefully develops what he thinks is the most charitable reconstruction of the design argument, and proceeds to show why it is defective for intrinsic reasons (for earlier version of this argument, see Sober 1999, 2002). Sober argues that the design argument can be rejected even without the need to consider alternative explanations for adaptive complexity (Sober 2008, 126): 'To see why the design argument is defective, there is no need to have a view as to whether Darwin’s theory of evolution is true' (Sober 2008, 154).
I simply would not accede to being forced into this, and would frequently be kept out of classes because of irreverent comments and mocking this religious stuff. Frankly, it stayed with me to this day. In fact, don't get me going. I'm almost as bad as Richard Dawkins on this issue.
But just in proportion as this process of extermination has acted on an enormous scale, so must the number of intermediate varieties, which have formerly existed, be truly enormous. Why then is not every geological formation and every stratum full of such intermediate links? Geology assuredly does not reveal any such finely graduated organic chain; and this, perhaps, is the most obvious and serious objection which can be urged against the theory. The explanation lies, as I believe, in the extreme imperfection of the geological record.
Individual humans are not super, but the organism of which we are all tiny cellular parts is most certainly that. The life-form that's so big we forget it's there, that turns minerals on its planet into tools to touch the infinite black gap between stars or probe the obliterating pressures at the bottom of the oceans. We are already part of a superbeing, a monster, a god, a living process that is so all encompassing that it is to an individual life what water is to a fish. We are cells in the body of a three-billion-year-old life-form whose roots are in the Precambrian oceans and whose genetic wiring extends through the living structures of everything on the planet, connecting everything that has ever lived in one immense nervous system.
it is high time we stop using the term “theory” while mentioning Evolution. The term “theory” somehow makes some people think of Evolution as an unproven “hypothesis”. Theory of Evolution is an incontrovertible fact of science. It is not a fictitious story like Creationism. It’s a hard reality. It is the bed-rock of Biology. Defying evolution means defying one’s own existence as a human being.
Evolution is promoted by its practitioners as more than mere science. Evolution is promulgated as an ideology, a secular religion -- a full-fledged alternative to Christianity, with meaning and morality. I am an ardent evolutionist and an ex-Christian, but I must admit that in this one complaint -- and Mr. Gish [Duane T. Gish the Creation Scientist] is but one of many to make it -- the literalists are absolutely right. Evolution is a religion. This was true of evolution in the beginning, and it is true of evolution still today.
What, after all, is so special about genes? The answer is that they are replicators. The laws of physics are supposed to be true all over the accessible universe. Are there any principles of biology which are likely to have similar universal validity? When astronauts voyage to distant planets and look for life, they can expect to find creatures too strange and unearthly for us to imagine. But is there anything which must be true of all life, wherever it is found, and whatever the basis of its chemistry? If forms of life exist whose chemistry is based on silicon rather than carbon, or ammonia rather than water, if creatures are discovered which boil to death at -100 degrees centigrade, if a form of life is found which is not based on chemistry at all, but on electronic reverberating circuits, will there still be any general principle which is true of all life? Obviously I do not know but, if I had to bet, I would put my money on one fundamental principle. This is the law that all life evolves by the differential survival of replicating entities. The gene, the DNA molecule, happens to be the replicating entity which prevails on our own planet. There may be others. If there are, provided certain conditions are met, they will almost inevitably tend to become the basis for an evolutionary process.
The essential quality that an entity needs, if it is to become an effective gene vehicle, is this. It must have an impartial exit channel into the future, for all the genes inside it. This is true of an individual wolf. The channel is the thin stream of sperms, or eggs, which it manufactures by meiosis. It is not true of the pack of wolves. Genes have something to gain from selfishly promoting the welfare of their own individual bodies, at the expense of other genes in the wolf pack. A bee-hive, when it swarms, appears to reproduce by broad-fronted budding, like a wolf pack. But if we look more carefully we find that, as far as the genes are concerned, their destiny is largely shared. The future of the genes in the swarm is, at least to a large extent, lodged in the ovaries of one queen. This is why—it is just another way of expressing the message of earlier chapters—the bee colony looks and behaves like a truly integrated single vehicle.
If about a dozen genera of birds had become extinct or were unknown, who would have ventured to have surmised that birds might have existed which used their wings solely as flappers, like the logger-headed duck (Micropterus of Eyton); as fins in the water and front legs on the land, like the penguin; as sails, like the ostrich; and functionally for no purpose, like the Apteryx. Yet the structure of each of these birds is good for it, under the conditions of life to which it is exposed, for each has to live by a struggle; but it is not necessarily the best possible under all possible conditions. It must not be inferred from these remarks that any of the grades of wing-structure here alluded to, which perhaps may all have resulted from disuse, indicate the natural steps by which birds have acquired their perfect power of flight; but they serve, at least, to show what diversified means of transition are possible.
All social animals, including people, live under constant pressure from two competing interests: protecting themselves from others and aligning themselves with others. When these two interests are balanced, the result is dynamic social homeostasis.
Far from being the smartest possible biological species, we are probably better thought of as the stupidest possible biological species capable of starting a technological civilization - a niche we filled because we got there first, not because we are in any sense optimally adapted to it.
Black magic, the magic of the primeval chaos, blots out or transmogrifies the true form of things. At the stroke of twelve the princess must flee the banquet or risk discovery in the rags of a kitchen wench; coach reverts to pumpkin. Instability lies at the heart of the world. With uncanny foresight folklore has long toyed symbolically with what the nineteenth century was to proclaim a reality - namely, that form is an illusion of the time dimension, that the magic flight of the pursued hero or heroine through frogskin and wolf coat has been, and will continue to be, the flight of all men.
The practice of that which is ethically best—what we call goodness or virtue—involves a course of conduct which, in all respects, is opposed to that which leads to success in the cosmic struggle for existence. In place of ruthless self-assertion it demands self-restraint; in place of thrusting aside, or treading down, all competitors, it requires that the individual shall not merely respect, but shall help his fellows... It repudiates the gladiatorial theory of existence... Laws and moral precepts are directed to the end of curbing the cosmic process.
Few scientists acquainted with the chemistry of biological systems at the molecular level can avoid being inspired. Evolution has produced chemical compounds exquisitely organized to accomplish the most complicated and delicate of tasks. Many organic chemists viewing crystal structures of enzyme systems or nucleic acids and knowing the marvels of specificity of the immune systems must dream of designing and synthesizing simpler organic compounds that imitate working features of these naturally occurring compounds.
The question of the position of man, as an animal, has given rise to much disputation, with the result of proving that there is no anatomical or developmental character by which he is more widely distinguished from the group of animals most nearly allied to him, than they are from one another.
There can be no doubt that the existing Fauna and Flora is but the last term of a long series of equally numerous contemporary species, which have succeeded one another, by the slow and gradual substitution of species for species, in the vast interval of time which has elapsed between the deposition of the earliest fossiliferous strata and the present day.
All organisms vary. It is in the highest degree improbable that any given variety should have exactly the same relations to surrounding conditions as the parent stock. In that case it is either better fitted (when the variation may be called useful), or worse fitted, to cope with them. If better, it will tend to supplant the parent stock; if worse, it will tend to be extinguished by the parent stock.If (as is hardly conceivable) the new variety is so perfectly adapted to the conditions that no improvement upon it is possible,—it will persist, because, though it does not cease to vary, the varieties will be inferior to itself.If, as is more probable, the new variety is by no means perfectly adapted to its conditions, but only fairly well adapted to them, it will persist, so long as none of the varieties which it throws off are better adapted than itself.On the other hand, as soon as it varies in a useful way, i.e. when the variation is such as to adapt it more perfectly to its conditions, the fresh variety will tend to supplant the former.
Every day, hundreds of observations and experiments pour into the hopper of the scientific literature. Many of them don't have much to do with evolution - they're observations about the details of physiology, biochemistry, development, and so on - but many of them do. And every fact that has something to do with evolution confirms its truth. Every fossil that we find, every DNA molecule that we sequence, every organ system that we dissect, supports the idea that species evolved from common ancestors. Despite innumerable possible observations that could prove evolution untrue, we don't have a single one. We don't find mammals in Precambrian rocks, humans in the same layers as dinosaurs, or any other fossils out of evolutionary order. DNA sequencing supports the evolutionary relationships of species originally deduced from the fossil record. And, as natural selection predicts, we find no species with adaptations that only benefit a different species. We do find dead genes and vestigial organs, incomprehensible under the idea of special creation. Despite a million chances to be wrong, evolution always comes up right. That is as close as we can get to a scientific truth.
The tendency to variation in living beings, which all admitted as a matter of fact; the selective influence of conditions, which no one could deny to be a matter of fact, when his attention was drawn to the evidence; and the occurrence of great geological changes which also was matter of fact; could be used as the only necessary postulates of a theory of the evolution of plants and animals which, even if not at once, competent to explain all the known facts of biological science, could not be shown to be inconsistent with any.
The fundamental biological variant is DNA. That is why Mendel's definition of the gene as the unvarying bearer of hereditary traits, its chemical identification by Avery (confirmed by Hershey), and the elucidation by Watson and Crick of the structural basis of its replicative invariance, are without any doubt the most important discoveries ever made in biology. To this must be added the theory of natural selection, whose certainty and full significance were established only by those later theories.
When one ponders on the tremendous journey of evolution over the past three billion years or so, the prodigious wealth of structures it has engendered, and the extraordinarily effective teleonomic performances of living beings from bacteria to man, one may well find oneself beginning to doubt again whether all this could conceivably be the product of an enormous lottery presided over by natural selection, blindly picking the rare winners from among numbers drawn at random. [Nevertheless,] a detailed review of the accumulated modern evidence [shows] that this conception alone is compatible with the facts.
Even today a good many distinguished minds seem unable to accept or even to understand that from a source of noise natural selection alone and unaided could have drawn all the music of the biosphere. In effect natural selection operates upon the products of chance and can feed nowhere else; but it operates in a domain of very demanding conditions, and from this domain chance is barred. It is not to chance but to these conditions that evolution owes its generally progressive course, its successive conquests, and the impression it gives of a smooth and steady unfolding.
(Evolution) general condition to which all theories, all hypotheses, all systems must bow and which they must satisfy henceforward if they are to be thinkable and true. Evolution is a light which illuminates all facts, a curve that all lines must follow.
An evolutionary perspective of our place in the history of the earth reminds us that Homo sapiens sapiens has occupied the planet for the tiniest fraction of that planet's four and a half thousand million years of existence. In many ways we are a biological accident, the product of countless propitious circumstances. As we peer back through the fossil record, through layer upon layer of long-extinct species, many of which thrived far longer than the human species is ever likely to do, we are reminded of our mortality as a species. There is no law that declares the human animal to be different, as seen in this broad biological perspective, from any other animal. There is no law that declares the human species to be immortal.
The evolution of life, and the evolutionary origin of mankind, are scientifically established as firmly and completely as any historical event not witnessed by human observers. Any concession to anti-evolutionists, suggesting that there are scientific reasons to doubt the facticity of evolution, would be propagating a plain untruth.
An example of such emergent phenomena is the origin of life from non-living chemical compounds in the oldest, lifeless oceans of the earth. Here, aided by the radiation energy received from the sun, countless chemical materials were synthesized and accumulated in such a way that they constituted, as it were, a primeval “soup.” In this primeval soup, by infinite variations of lifeless growth and decay of substances during some billions of years, the way of life was ultimately reached, with its metabolism characterized by selective assimilation and dissimilation as end stations of a sluiced and canalized flow of free chemical energy.
For three million years we were hunter-gatherers, and it was through the evolutionary pressures of that way of life that a brain so adaptable and so creative eventually emerged. Today we stand with the brains of hunter-gatherers in our heads, looking out on a modern world made comfortable for some by the fruits of human inventiveness, and made miserable for others by the scandal of deprivation in the midst of plenty.
Evolution is a blind giant who rolls a snowball down a hill. The ball is made of flakes—circumstances. They contribute to the mass without knowing it. They adhere without intention, and without foreseeing what is to result. When they see the result they marvel at the monster ball and wonder how the contriving of it came to be originally thought out and planned. Whereas there was no such planning, there was only a law: the ball once started, all the circumstances that happened to lie in its path would help to build it, in spite of themselves.
Evolution is the law of policies: Darwin said it, Socrates endorsed it, Cuvier proved it and established it for all time in his paper on 'The Survival of the Fittest.' These are illustrious names, this is a mighty doctrine: nothing can ever remove it from its firm base, nothing dissolve it, but evolution.
I have been scientifically studying the traits and dispositions of the “lower animals” (so-called,) and contrasting them with the traits and dispositions of man. I find the result profoundly humiliating to me. For it obliges me to renounce my allegiance to the Darwinian theory of the Ascent of Man from the Lower Animals; since it now seems plain to me that that theory ought to be vacated in favor of a new and truer one, this new and truer one to be named the Descent of Man from the Higher Animals.
I fully agree with all that you say on the advantages of H. Spencer's excellent expression of 'the survival of the fittest.' This, however, had not occurred to me till reading your letter. It is, however, a great objection to this term that it cannot be used as a substantive governing a verb; and that this is a real objection I infer from H. Spencer continually using the words, natural selection.(Letter to A. R. Wallace July 1866)
It is not the organs—that is, the character and form of the animal's bodily parts—that have given rise to its habits and particular structures. It is the habits and manner of life and the conditions in which its ancestors lived that have in the course of time fashioned its bodily form, its organs and qualities.
The uniformity of the earth's life, more astonishing than its diversity, is accountable by the high probability that we derived, originally, from some single cell, fertilized in a bolt of lightning as the earth cooled. It is from the progeny of this parent cell that we take our looks; we still share genes around, and the resemblance of the enzymes of grasses to those of whales is a family resemblance.
As Karl Marx once noted: 'Hegel remarks somewhere that all great, world-historical facts and personages occur, as it were, twice. He forgot to add: the first time as tragedy, the second as farce.' William Jennings Bryan and the Scopes trial was a tragedy. The creationists and intelligent design theorists are a farce.
When in 1863 Thomas Huxley coined the phrase 'Man's Place in Nature,' it was to name a short collection of his essays applying to man Darwin's theory of evolution. The Origin of Species had been published only four years before, and the thesis that man was literally a part of nature, rather than an earthy vessel charged with some sublimer stuff, was so novel and so offensive to current metaphysics that it needed the most vigorous defense. Half the civilized world was rudely shocked, the other half skeptically amused.Nearly a century has passed since the Origin shattered the complacency of the Victorian world and initiated what may be called the Darwinian revolution, an upheaval of man's ideas comparable to and probably exceeding in significance the revolution that issued from Copernicus's demonstration that the earth moves around the sun. The theory of evolution was but one of many factors contributing to the destruction of the ancient beliefs; it only toppled over what had already been weakened by centuries of decay, rendered suspect by the assaults of many intellectual disciplines; but it marked the beginning of the end of the era of faith.
Quite recently the human descent theory has been stigmatized as the 'gorilla theory of human ancestry.' All this despite the fact that Darwin himself, in the days when not a single bit of evidence regarding the fossil ancestors of man was recognized, distinctly stated that none of the known anthropoid apes, much less any of the known monkeys, should be considered in any way as ancestral to the human stock.
The Earth Speaks, clearly, distinctly, and, in many of the realms of Nature, loudly, to William Jennings Bryan, but he fails to hear a single sound. The earth speaks from the remotest periods in its wonderful life history in the Archaeozoic Age, when it reveals only a few tissues of its primitive plants. Fifty million years ago it begins to speak as 'the waters bring forth abundantly the moving creatures that hath life.' In successive eons of time the various kinds of animals leave their remains in the rocks which compose the deeper layers of the earth, and when the rocks are laid bare by wind, frost, and storm we find wondrous lines of ascent invariably following the principles of creative evolution, whereby the simpler and more lowly forms always precede the higher and more specialized forms.The earth speaks not of a succession of distinct creations but of a continuous ascent, in which, as the millions of years roll by, increasing perfection of structure and beauty of form are found; out of the water-breathing fish arises the air-breathing amphibian; out of the land-living amphibian arises the land-living, air-breathing reptile, these two kinds of creeping things resembling each other closely. The earth speaks loudly and clearly of the ascent of the bird from one kind of reptile and of the mammal from another kind of reptile.
The living cell is the most complex system of its size known to mankind. Its host of specialized molecules, many found nowhere else but within living material, are themselves already enormously complex. They execute a dance of exquisite fidelity, orchestrated with breathtaking precision. Vastly more elaborate than the most complicated ballet, the dance of life encompasses countless molecular performers in synergetic coordination. Yet this is a dance with no sign of a choreographer. No intelligent supervisor, no mystic force, no conscious controlling agency swings the molecules into place at the right time, chooses the appropriate players, closes the links, uncouples the partners, moves them on. The dance of life is spontaneous, self-sustaining, and self-creating.
The male frog, in mating season," said Crake, "makes as much noise as it can. The females are attracted to the male frog with the biggest, deepest voice because it suggests a more powerful frog, one with superior genes. Small male frogs - it's been documented - discover that if they position themselves in empty drainpipes, the pipe acts as a voice amplifier, and the small frog appears much larger than it really is.""So?""So that's what art is, for the artist," said Crake. "An empty drainpipe. An amplifier. A stab at getting laid.""Your analogy falls down when it comes to female artists," said Jimmy. "They're not in it to get laid. They'd gain no biological advantage from amplifying themselves, since potential mates would be deterred rather than attracted by this sort of amplification. Men aren't frogs, they don't want women who are ten times bigger than them.""Female artists are biologically confused," said Crake.
A biochemist colleague has kindly provided me with a bottle of hydrogen peroxide, and enough hydroquinone for 50 bombardier beetles, I am now about to mix the two together. According to the above, they will explode in my face. Here goes...Well... I'm still here! I poured the hydrogen peroxide into the hydroquinone, and absolutely nothing happened. It didn't event get warm!
We should not be too quick to dismiss our own [ocular] arrangement. As so often in biology, the situation is more complex.....we have the advantage that our own light-sensitive cells are embedded directly in their support cells (the retinal pigment epithelium) with an excellent blood supply immediately underneath. Such an arrangement supports the continuous turnover of photosensitive pigments. The human retina consumes even more oxygen than the brain, per gram, making it the most energetic organ in the body.
The idea of decimation as a lottery converts the new iconography of the Burgess Shale into a radical view about the pathways of life and the nature of history. ... May our poor and improbable species find joy in its new-found fragility and good fortune! Wouldn't anyone with the slightest sense of adventure, or the most weakly flickering respect for intellect, gladly exchange the old cosmic comfort for a look at something so weird and wonderful - yet so real - as *Opabinia*?
Now the leatherback turtle overcame the heat issue via a simple, but evolutionarily impossible solution; it is the only reptile that possesses fatty insulation known as brown adipose tissue, and the only reptile that regulates a high body temperature. This brown adipose tissue is the expression of the UCP1 gene, and, aside from the leatherbacks, is found only in mammals, amphibians, and fishes. Not one other reptile has UCP1.
An irrefutable proof that such single-celled primaeval animals really existed as the direct ancestors of Man, is furnished according to the fundamental law of biogeny by the fact that the human egg is nothing more than a simple cell.
The ancestors of the higher animals must be regarded as one-celled beings, similar to the Amoebae which at the present day occur in our rivers, pools, and lakes. The incontrovertible fact that each human individual develops from an egg, which, in common with those of all animals, is a simple cell, most clearly proves that the most remote ancestors of man were primordial animals of this sort, of a form equivalent to a simple cell. When, therefore, the theory of the animal descent of man is condemned as a 'horrible, shocking, and immoral' doctrine, tho unalterable fact, which can be proved at any moment under the microscope, that the human egg is a simple cell, which is in no way different to those of other mammals, must equally be pronounced 'horrible, shocking, and immoral.
...if an organised body is not in the situation and circumstances best adapted to its sustenance and propagation, then, in conceiving an indefinite variety among the individuals of that species, we must be assured, that, on the one hand, those which depart most from the best adapted constitution, will be the most liable to perish, while, on the other hand, those organised bodies, which most approach to the best constitution for the present circumstances, will be best adapted to continue, in preserving themselves and multiplying the individuals of their race.
Evidently neither cats nor dogs, nor other animals that listen to human music, were constituted for the appreciation of it, for it is not of the slightest use to them in the struggle for existence. Moreover, they and their organs of hearing were much older than man and his music. Their power of appreciating music is therefore an uncontemplated side-faculty of a hearing apparatus which has become on other grounds what we find it to be. So it is, I believe, with man. He has not acquired his musical hearing as such, but has received a highly developed organ of hearing by a process of selection, because it was necessary to him in the selective process ; and this organ of hearing happens also to be adapted to listening to music.
It was in the attempt to ascertain the interrelationships between species that experiments n genetics were first made. The words "evolution" and "origin of species" are now so intimately associated with the name of Darwin that we are apt to forger that the idea of common descent had been prominent in the mnds of naturalists before he wrote, and that, for more than half a century, zealous investigators had been devoting themselves to the experimental study of that possibility. Prominent among this group of experimenters may be mentioned Koelreauter, John Hunter, Herbert Knight, Gartner, Jordan. Naudin, Godron, Lecoq, Wichura--men whose names are familiar to every reader of Animals and Plants unders Domestication.
As long as museums and universities send out expeditions to bring to light new forms of living and extinct animals and new data illustrating the interrelations of organisms and their environments, as long as anatomists desire a broad comparative basis human for anatomy, as long as even a few students feel a strong curiosity to learn about the course of evolution and relationships of animals, the old problems of taxonomy, phylogeny and evolution will gradually reassert themselves even in competition with brilliant and highly fruitful laboratory studies in cytology, genetics and physiological chemistry.
More about the selection theory: Jerne meant that the Socratic idea of learning was a fitting analogy for 'the logical basis of the selective theories of antibody formation': Can the truth (the capability to synthesize an antibody) be learned? If so, it must be assumed not to pre-exist; to be learned, it must be acquired. We are thus confronted with the difficulty to which Socrates calls attention in Meno [ ... ] namely, that it makes as little sense to search for what one does not know as to search for what one knows; what one knows, one cannot search for, since one knows it already, and what one does not know, one cannot search for, since one does not even know what to search for. Socrates resolves this difficulty by postulating that learning is nothing but recollection. The truth (the capability to synthesize an antibody) cannot be brought in, but was already inherent.
Darwin's theory was received in Russia with profound sympathy. While in Western Europe it met firmly established old traditions which it had first to overcome, in Russia its appearance coincided with the awakening of our society after the Crimean War and here it immediately received the status of full citizenship and ever since has enjoyed widespread popularity.
First LawIn every animal which has not passed the limit of its development, a more frequent and continuous use of any organ gradually strengthens, develops and enlarges that organ, and gives it a power proportional to the length of time it has been so used; while the permanent disuse of any organ imperceptibly weakens and deteriorates it, and progressively diminishes its functional capacity, until it finally disappears.Second LawAll the acquisitions or losses wrought by nature on individuals, through the influence of the environment in which their race has long been placed, and hence through the influence of the predominant use or permanent disuse of any organ; all these are preserved by reproduction to the new individuals which arise, provided that the acquired modifications are common to both sexes, or at least to the individuals which produce the young.
Living organisms were not independently created, but have descended and diversified over time from common ancestors. And thus, no other biological theory so elegantly explains this. Evolutionary theory has withstood the test of time—by way of vicarious experimentation, observation, analysis, and relentless criticism, though opposing viewpoints still cling to the concept of "design." As a person of the biological sciences, I cannot subscribe to such misguided notions that suggest static biological states. Clearly, proper examination of the natural world reveal evolutionary trajectories—some random, others nonrandom—and all having observable genetic implications. It is only when we apply evolutionary explanations to living systems that it becomes ever so clear. The world was not specifically designed with us in mind, but rather we long since adapted and conformed to our surroundings, only giving it the illusionary appearance of "design.
Each species may have had its origin in a single pair, or individual, where an individual was sufficient, and species may have been created in succession at such times and in such places as to enable them to multiply and endure for an appointed period, and occupy an appointed space on the globe.
Objectivity cannot be equated with mental blankness; rather, objectivity resides in recognizing your preferences and then subjecting them to especially harsh scrutiny — and also in a willingness to revise or abandon your theories when the tests fail (as they usually do).
Might one not say that in the chance combination of nature's production, since only those endowed with certain relations of suitability could survive, it is no cause for wonder that this suitability is found in all species that exist today? Chance, one might say, produced an innumerable multitude of individuals; a small number turned out to be constructed in such fashion that the parts of the animal could satisfy its needs; in another, infinitely greater number, there was neither suitability nor order: all of the later have perished; animals without a mouth could not live, others lacking organs for reproduction could not perpetuate themselves: the only ones to have remained are those in which were found order and suitability; and these species, which we see today, are only the smallest part of what blind fate produced.
Man wants to see nature and evolution as separate from human activities. There is a natural world, and there is man. But man also belongs to the natural world. If he is a ferocious predator, that too is part of evolution. If cod and haddock and other species cannot survive because man kills them, something more adaptable will take their place. Nature, the ultimate pragmatist, doggedly searches for something that works. But as the cockroach demonstrates, what works best in nature does not always appeal to us.
This little book has been written in the hope that it may appeal to several classes of readers.Not infrequently I have been asked by friends of different callings in life to recommend them some book on mimicry which shall be reasonably short, well illustrated without being very costly, and not too hard to understand. I have always been obliged to tell them that I know of nothing in our language answering to this description, and it is largely as an attempt to remedy this deficiency that the present little volume has been written.
In the absence of data, we will always make up stories. In fact, the need to make up a story, especially when we are hurt, is part of our most primitive survival wiring. Mean making is in our biology, and our default is often to come up with a story that makes sense, feels familiar, and offers us insight into how best to self-protect.
When I realized that my home was completely filled with a biologically toxic radio wave field, I decided that the best route forward was to milk the home for all of the biological research that I could possibly produce from it!
When you look more generally at life on Earth, you find that it is all the same kind of life. There are not many different kinds; there's only one kind. It uses about fifty fundamental biological building blocks, organic molecules.
A sound Physics of the Earth should include all the primary considerations of the earth's atmosphere, of the characteristics and continual changes of the earth's external crust, and finally of the origin and development of living organisms. These considerations naturally divide the physics of the earth into three essential parts, the first being a theory of the atmosphere, or Meteorology, the second, a theory of the earth's external crust, or Hydrogeology, and the third, a theory of living organisms, or Biology.
A recognized fact which goes back to the earliest times is that every living organism is not the sum of a multitude of unitary processes, but is, by virtue of interrelationships and of higher and lower levels of control, an unbroken unity. When research, in the efforts of bringing understanding, as a rule examines isolated processes and studies them, these must of necessity be removed from their context. In general, viewed biologically, this experimental separation involves a sacrifice. In fact, quantitative findings of any material and energy changes preserve their full context only through their being seen and understood as parts of a natural order.
A multitude of harlequin lifeforms bobbed and twirled and played in the depths of the Atlantic. Pink cucumbers with thorny backs. Algae. Starfish. Annelids with simple brains and a hundred toes. Sponges—like yellow, swollen hands—sucked in water and pushed out oxygen. Most amusing were the mysterious buggers who had no likeness on the previous earth; tiny beasts with exotic exoskeletons engraved with deep grid-like patterns, snails with horns, and slithering plants that looked like magenta weeping willows.
The beauty in the genome is of course that it's so small. The human genome is only on the order of a gigabyte of data...which is a tiny little database. If you take the entire living biosphere, that's the assemblage of 20 million species or so that constitute all the living creatures on the planet, and you have a genome for every species the total is still about one petabyte, that's a million gigabytes - that's still very small compared with Google or the Wikipedia and it's a database that you can easily put in a small room, easily transmit from one place to another. And somehow mother nature manages to create this incredible biosphere, to create this incredibly rich environment of animals and plants with this amazingly small amount of data.
Nature, ... in order to carry out the marvelous operations [that occur] in animals and plants has been pleased to construct their organized bodies with a very large number of machines, which are of necessity made up of extremely minute parts so shaped and situated as to form a marvelous organ, the structure and composition of which are usually invisible to the naked eye without the aid of a microscope. ... Just as Nature deserves praise and admiration for making machines so small, so too the physician who observes them to the best of his ability is worthy of praise, not blame, for he must also correct and repair these machines as well as he can every time they get out of order.
Some believe what separates men from animals is our ability to reason. Others say it’s language or romantic love, or opposable thumbs. Living here in this lost world, I’ve come to believe it is more than our biology. What truly makes us human is our unending search, our abiding desire for immortality.
We all start out the same in our mothers' wombs. We, all of us, when floating in the amniotic sea of our earliest oblivion, have gonads. If the Y chromosome didn't swoop in to act on the gonads of some of us and make testes, we would all become women. In biology, the Genesis story is reversed: Adam becomes Adam out of Eve, not the other way around.
I stepped to the tank's edge, leaned in, and concentrated on keeping my eyes open. Which fish would be the shooter? The fish were all facing me, but one in particular seemed to be staring directly at my left eye, like a hunter targeting his prey. Wham! The water hit my pupil with such force that I jerked back …. Laughing, I wiped my left eye but stayed by the tank, my left hand resting on its edge. Another fish quickly seized the opportunity to blast the diamond in my engagement ring, while a third targeted the red carnelian stone in my earring, and yet another shot my right eye.
An infinity of these tiny animals defoliate our plants, our trees, our fruits... they attack our houses, our fabrics, our furniture, our clothing, our furs ... He who in studying all the different species of insects that are injurious to us, would seek means of preventing them from harming us, would seek to cause them to perish, proposes for his goal important tasks indeed.
I know that certain minds would regard as audacious the idea of relating the laws which preside over the play of our organs to those laws which govern inanimate bodies; but, although novel, this truth is none the less incontestable. To hold that the phenomena of life are entirely distinct from the general phenomena of nature is to commit a grave error, it is to oppose the continued progress of science.
...Why is it, that from the moment you enter medical school to the moment you retire, that the only disorder you will ever diagnosis with a physics book - is obesity? This is biology folks, it's endocrinology, it's physiology - physics has nothing to do with it. The law of thermodynamics is always true, [but] the energy balance equation is irrelevant...
I submit a body of facts which cannot be invalidated. My opinions may be doubted, denied, or approved, according as they conflict or agree with the opinions of each individual who may read them; but their worth will be best determined by the foundation on which they rest—the incontrovertible facts.
It necessarily follows that chance alone is at the source of every innovation, and of all creation in the biosphere. Pure chance, absolutely free but blind, at the very root of the stupendous edifice of evolution: this central concept of modern biology is no longer one among many other possible or even conceivable hypotheses. It is today the sole conceivable hypothesis, the only one that squares with observed and tested fact. And nothing warrants the supposition - or the hope - that on this score our position is ever likely to be revised. There is no scientific concept, in any of the sciences, more destructive of anthropocentrism than this one.
The attention given to the side of the head which has received the injury, in connection with a specific reference to the side of the body nervously affected, is in itself evidence that in this case the ancient surgeon was already beginning observations on the localization of functions in the brain.
The fate of the physiology of the brain is independent of the truth and falsity of my assertions relative to the laws of the organization of the nervous system, in general, and of the brain in particular, just as the knowledge of the functions of a sense is independent of the knowledge of the structure of its apparatus.
Our brains contain one hundred billion nerve cells (neurons). Each neuron makes links with ten thousand other neurons to form an incredible three dimensional grid. This grid therefore contains a thousand trillion connections - that's 1,000,000,000,000,000 (a quadrillion). It's hard to imagine this, so let's visualise each connection as a disc that's 1mm thick. Stack up the quadrillion discs on top of each other and they will reach the sun (which is ninety-three million miles from the earth) and back, three times over.
Not untill all babies are born from glass jars will the combat cease between mother and son. But in a totalitarian future that has removed procreation from woman's hands, there will also be no affect and no art. Men will be machines, without pain but also without pleasure. Imagination has a price, which we are paying every day. There is no escape from the biologic chains that bind us.
I would like to start by emphasizing the importance of surfaces. It is at a surface where many of our most interesting and useful phenomena occur. We live for example on the surface of a planet. It is at a surface where the catalysis of chemical reactions occur. It is essentially at a surface of a plant that sunlight is converted to a sugar. In electronics, most if not all active circuit elements involve non-equilibrium phenomena occurring at surfaces. Much of biology is concerned with reactions at a surface.
The Everglades was the only place on earth where alligators (broad snout, fresh water, darker skin) and crocodiles (pointy snout, salt water, toothy grin) lived side by side. It was the only home of the Everglades mink, Okeechobee gourd, and Big Cypress fox squirrel. It had carnivorous plants, amphibious birds, oysters that grew on trees, cacti that grew in water, lizards that changed colors, and fish that changed genders. It had 1,100 species of trees and plants, 350 birds, and 52 varieties of porcelain-smooth, candy-striped tree snails. It had bottlenose dolphins, marsh rabbits, ghost orchids, moray eels, bald eagles, and countless other species that didn't seem to belong on the same continent, much less in the same ecosystem.
Carson was persuaded that many experts either failed to recognize or chose to ignore the potential hazards of pesticides. She was convinced that the weight of her scientific evidence would defeat the skeptics among them. And once the public had the necessary information, citizens could make informed decisions about what Carson believed was a matter of life and death.
She could not be silent even if the men of science, many of them smug experts in white lab coats who promised “better living through chemistry,” dismissed her warnings as feminine hysteria.
Much of the geographical work of the past hundred years... has either explicitly or implicitly taken its inspiration from biology, and in particular Darwin. Many of the original Darwinians, such as Hooker, Wallace, Huxley, Bates, and Darwin himself, were actively concerned with geographical exploration, and it was largely facts of geographical distribution in a spatial setting which provided Darwin with the germ of his theory.
I studied calculus for the first time, which to me was an amazingly empowering experience which I could really see how you could understand all sorts of things, and I decided that chemistry and biology just had too much memory for me to be interested. Physics was very easy.
In a sense, the Earth is mounting an immune response against the human species. It is beginning to react to the human parasite, the flooding infection of people, the dead spots of the concrete all over the planet, the cancerous rot-outs in Europe, Japan and the United States, thick with replicating primates, the colonies enlarging and spreading and threatening to shock the biosphere with mass extinctions. Perhaps the biosphere does not 'like' the idea of five billion humans.
It has been demonstrated that a species of penicillium produces in culture a very powerful antibacterial substance which affects different bacteria in different degrees. Generally speaking it may be said that the least sensitive bacteria are the Gram-negative bacilli, and the most susceptible are the pyogenic cocci ... In addition to its possible use in the treatment of bacterial infections penicillin is certainly useful... for its power of inhibiting unwanted microbes in bacterial cultures so that penicillin insensitive bacteria can readily be isolated.
It is shown that the golden ratio plays a prominent role in the dimensions of all objects which exhibit five-fold symmetry. It is also showed that among the irrational numbers, the golden ratio is the most irrational and, as a result, has unique applications in number theory, search algorithms, the minimization of functions, network theory, the atomic structure of certain materials and the growth of biological organisms.
Similarities are read into nature by our nervous system, and so are structurally less fundamental than differences. Less fundamental, but no less important, as life and 'intelligence' would be totally impossible without abstracting. It becomes clear that the problem which has so excited the s.r. of the people of the United States of America and added so much to the merriment of mankind, 'Is the evolution a ''fact'' or a ''theory''?, is simply silly. Father and son are never identical - that surely is a structural 'fact' - so there is no need to worry about still higher abstractions, like 'man' and 'monkey'. That the fanatical and ignorant attack on the theory of evolution should have occured may be pathetic, but need concern us little, as such ignorant attacks are always liable to occur. But that biologists should offer 'defences' based on the confusions of orders of abstractiobs, and that 'philosophers' should have failed to see the simple dependence is rather sad. The problems of 'evolution' are verbal and have nothing to do with life as such, which is made up all through of different individuals, 'similarity' being structurally a manufactured article, produced by the nervous system of the observer.
Stalin’s teachings about gradual, concealed, unnoticeable quantitative changes leading to rapid, radical, qualitative changes permitted Soviet biologists to discover in plants the realization of such qualitative transitions that one species could be transformed into another’… The slide away from truth-directed science had disastrous results in agriculture. It was also humanly disastrous. Biologists who disagreed were shot or imprisoned.
They are near the bottom of the food chain - a meal for fish and birds - while humans eat from the top of the food chain, consuming an astonishing array of what lies on the planet. But eventually, even we become food for the worms. Shakespeare saw this connection, writing in Hamlet, "A man may fish with a worm that hath eat of a king, and eat of a fish that hath fed of that worm.
Oxygen deprivation and supplemental oxygen are both bio-hazards for Mauna Kea workers
People, as curious primates, dote on concrete objects that can be seen and fondled. God dwells among the details, not in the realm of pure generality. We must tackle and grasp the larger, encompassing themes of our universe, but we make our best approach through small curiosities that rivet our attention - all those pretty pebbles on the shoreline of knowledge. For the ocean of truth washes over the pebbles with every wave, and they rattle and clink with the most wondrous din.
As the physicist Paul Davies puts it, 'If everything needs everything else, how did the communities of molecules ever arise in the first place?' It is rather as if all the ingredients in your kitchen somehow got together and baked themselves into a cake - but a cake that could moreover divide when necessary to produce more cakes. It is little wonder that we call it the miracle of life. It is also little wonder that we have barely begun to understand it.
Of the contributions made during the essayist period three call for notice: Weismann deserves mention for his useful work in asking for the proof that "acquired characters" or, to speak more precisely, parental experience can really be transmitted to the offspring. The ocurrence of progressive adaptation by transmission of effects of use had seemed so natural to Darwin and his contemporaries that no proof of the physiological reality of the henomenon was thought necessary. Weismann's challenge revealed the utter inadequacy of the evidence on which the beliefs were based. They are doubtless isolated observations which may be interpreted as favouring the belief in these transmissions, but such meagre indications as exist are by general consent admitted to be too slight to be of much assistance in the attempt to understand how the more complex adaptive mechanisms arose.
I am above the forest region, amongst grand rocks & such a torrent as you see in Salvator Rosa's paintings vegetation all a scrub of rhodos. with Pines below me as thick & bad to get through as our Fuegian Fagi on the hill tops, & except the towering peaks of P. S. [perpetual snow] that, here shoot up on all hands there is little difference in the mt scenery—here however the blaze of Rhod. flowers and various colored jungle proclaims a differently constituted region in a naturalist's eye & twenty species here, to one there, always are asking me the vexed question, where do we come from?[Letter to Charles Darwin 24 Jun 1849]
Chloroplasts bear chlorophyll; they give the green world its color, and they carry out the business of photosynthesis. Around the inside perimeter of each gigantic cell trailed a continuous loop of these bright green dots. They spun . . . they pulsed, pressed, and thronged . . . they shone, they swarmed in ever-shifting files around and around the edge of the cell; they wandered, they charged, they milled, raced . . . they flowed and trooped greenly . . . All the green in the planted world consists of these whole, rounded chloroplasts . . . If you analyze a molecule of chlorophyll itself, what you get is one hundred thirty-six atoms of hydrogen, carbon, oxygen, and nitrogen arranged in an exact and complex relationship around a central ring. At the ring’s center is a single atom of magnesium. Now: If you remove the atom of magnesium and in its place put an atom of iron, you get a molecule of hemoglobin. The iron atom combines with all the other atoms to make red blood, the streaming red dots in the goldfish’s tail.
The woman who later became his wife was sleeping in his bed, her face buried in the pillows and her feet crossed on top of each other like a child's. He watched her sleep and struggled to see her as she was, but what he saw instead were her muscles and bones. He saw right through the skin to where her femur connected to her tibia by way of the ligaments, to the hair web of nerves and the delicate forest of her lungs, to the abstract heart pumping blood through her arteries. It terrified him how easily these systems could fail her.
There are species that retain their characteristics even in conditions that are relatively different from their natural ones; other species in similar circumstances instead become extinct; otherwise what takes place is racial mixing with other elements in which no assimilation or real evolution occurs. The result of this interbreeding closely resembles Mendel’s laws concerning heredity: once it disappears in the phenotype, the primitive element survives in the form of a separated, latent heredity that is capable of cropping up in sporadic apparitions, even though it is always endowed with a character of heterogeneity in regard to the superior type.
We cannot fathom the marvelous complexity of an organic being; but on the hypothesis here advanced this complexity is much increased. Each living creature must be looked at as a microcosm--a little universe, formed of a host of self-propagating organisms, inconceivably minute and as numerous as the stars in heaven.
One way of emphasizing the singularity of the recent past is [..] to observe that the total number of humans ever to have lived is estimated at around (a bit less than) 100 billion. One of Walt Whitman's poems has a memorable image—thinking of all past people lined up in orderly columns behind those living—‘row upon row rise the phantoms behind us’. Actually, looking over our shoulder, we would see only around 15 rows.
Biological databases impose particular limitations on how biological objects can be related to one another. In other words, the structure of a database predetermines the sorts of biological relationships that can be 'discovered'. To use the language of Bowker and Star, the database 'torques,' or twists, objects into particular conformations with respect to one another. The creation of a database generates a particular and rigid structure of relationships between biological objects, and these relationships guide biologists in thinking about how living systems work. The evolution of GenBank from flat-file to relational to federated database paralleled biologists' moves from gene-centric to alignment-centric to multielement views of biological action.
If you allow a creek to go back to being a creek, if you let the trees and the bramble get overgrown, and you let the stream overrun its banks whenever it wants to, the wetland will take care of itself. The water that trickles into the ocean will be clean and pristine if everything is just left alone to work the way it was designed to work. Earthworms have shown that they can take care of the soil in the same way that a wetland takes care of the water. Nature regenerates. It Cleans. It hides a multitude of sins.
In the ensuing chapters, we will look in some detail at particular manifestations of the modern scientific ideology and the false paths down which it has led us. We will consider how biological determinism has been used to explain and justify inequalities within and between societies and to claim that those inequalities can never be changed. We will see how a theory of human nature has been developed using Darwin's theory of evolution by natural selection to claim that social organization is also unchangeable because it is natural. We will see how problems of health and disease have been located within the individual so that the individual becomes a problem for society to cope with rather than society becoming a problem for the individual. And we will see how simple economic relationships masquerading as facts of nature can drive the entire direction of biological research and technology.
in human males, testosterone appears to promote behavior intended to dominate other people. This behavior can be expressed aggressively, even violently, as well as nonaggressively. Testosterone levels, even a single baseline measurement, correlate well with dominance behavior, that is, testosterone not only affects dominance behavior but also responds to it.
winning or losing an agonist encounter has a dramatic impact on future aggressive behavior. Winners are more likely to initiate attacks against unknown opponents, whereas losers are more circumspect and likely to retreat from unfamiliar conspecifics, adopting an opportunistic strategy, picking and choosing their fights. In the worst case scenario, animals socially subjugated by constant threat and attack from dominant conspecifics develop a submissive phenotype, showing little or no aggressive behavior, essentially eliminating themselves from the gene pool.
It is often thought that the life of the hunter-gatherer was one of feast and famine. But most available data suggest that they were surprisingly healthy and had a fairly stable diet and lifestyle. Not so the primitive farmers. In years when the crops failed, in settlements where the population density was high and where disease weakened the ability to cope even further, life would have been very hard indeed. The settled population could not migrate to follow the food supply as could hunter-gatherers. They were trapped.
In bodies, a movement anywhere will send out a wave of response through the structure: the whole body participates, and the better organized it is around the skeletal core, the more clearly it reverberates. A person whose musculature is either slack or bound by excessive tension cannot act either as delicately or as powerfully as one that reverberates more freely.
Wilson (1975) defines biological communication relatively broadly as 'the action on the part of one organism (or cell) that alters the probability pattern of behavior in another organism (or cell) in a fashion adaptive to either one or both of the participants.
George Gey paid his way through a biology degree at the University of Pittsburgh by working as a carpenter and mason, and he could make nearly anything for cheap or free. During his second year in medical school, he rigged a microscope with a time-lapse motion picture camera to capture live cells on film. It was a Frankensteinish mishmash of microscope parts, glass, and 16-millimeter camera equipment from who knows where, plus metal scraps, and an old motor from Shapiro’s junkyard. He built it in a hole he’d blasted in the foundation of Hopkins, right below the morgue, its base entirely underground and surrounded by a thick wall of cork to keep it from jiggling when streetcars passed. At night, a Lithuanian lab assistant slept next to the camera on a cot, listening to its constant tick, making sure it stayed stable through the night, waking every hour to refocus it. With that camera, Gey and his mentor, Warren Lewis, filmed the growth of cells, a process so slow - like the growth of a flower - the naked eye couldn’t see it. They played the film at high speed so they could watch cell division on the screen in one smooth motion, like a story unfolding in a flip book.
It is also only in humans that aggression may be used to commit crimes, to enslave others or compel acquiescence to religious or ideological doctrine, or to pursue wars of national interest. At the individual level, men are universally more aggressive than women, and rates of aggressive confrontation are greatest among those who are young, poor, or unmarried. Cultural factors moderate human aggression as well, with men's heightened sensitivity to signs of disrespect, challenge, or threat spawning a high frequency of confrontational violence in so-called “cultures of honor”.
A nutritive centre, anatomically considered, is merely a cell, the nucleus of which is the permanent source of successive broods of young cells, which from time to time fill the cavity of their parent, and carrying with them the cell wall of the parent, pass off in certain directions, and under various forms, according to the texture or organ of which their parent forms a part.
In describing a protein it is now common to distinguish the primary, secondary and tertiary structures. The primary structure is simply the order, or sequence, of the amino-acid residues along the polypeptide chains. This was first determined by [Frederick] Sanger using chemical techniques for the protein insulin, and has since been elucidated for a number of peptides and, in part, for one or two other small proteins. The secondary structure is the type of folding, coiling or puckering adopted by the polypeptide chain: the a-helix structure and the pleated sheet are examples. Secondary structure has been assigned in broad outline to a number of librous proteins such as silk, keratin and collagen; but we are ignorant of the nature of the secondary structure of any globular protein. True, there is suggestive evidence, though as yet no proof, that a-helices occur in globular proteins, to an extent which is difficult to gauge quantitatively in any particular case. The tertiary structure is the way in which the folded or coiled polypeptide chains are disposed to form the protein molecule as a three-dimensional object, in space. The chemical and physical properties of a protein cannot be fully interpreted until all three levels of structure are understood, for these properties depend on the spatial relationships between the amino-acids, and these in turn depend on the tertiary and secondary structures as much as on the primary. Only X-ray diffraction methods seem capable, even in principle, of unravelling the tertiary and secondary structures.[Co-author with G. Bodo, H. M. Dintzis, R. G. Parrish, H. Wyckoff, and D. C. Phillips]
The deviation of man from the state in which he was originally placed by nature seems to have proved to him a prolific source of diseases. From the love of splendour, from the indulgences of luxury, and from his fondness for amusement he has familiarised himself with a great number of animals, which may not originally have been intended for his associates.The wolf, disarmed of ferocity, is now pillowed in the lady's lap. The cat, the little tiger of our island, whose natural home is the forest, is equally domesticated and caressed. The cow, the hog, the sheep, and the horse, are all, for a variety of purposes, brought under his care and dominion.
Branches or types are characterized by the plan of their structure,Classes, by the manner in which that plan is executed, as far as ways and means are concerned, Orders, by the degrees of complication of that structure, Families, by their form, as far as determined by structure, Genera, by the details of the execution in special parts, andSpecies, by the relations of individuals to one another and to the world in which they live, as well as by the proportions of their parts, their ornamentation, etc.
There are a lot of things animals do that we can't," she says, "like flying and camouflage, and we've adapted, through technology ... It's funny when people say something is natural, or not. Compared with what? Compared with when? It's this vanity of humans to think of themselves as special, as being at the height of evolution. We're not. We're obviously still adapting.
The extracellular genesis of cells in animals seemed to me, ever since the publication of the cell theory [of Schwann], just as unlikely as the spontaneous generation of organisms. These doubts produced my observations on the multiplication of blood cells by division in bird and mammalian embryos and on the division of muscle bundles in frog larvae. Since then I have continued these observations in frog larvae, where it is possible to follow the history of tissues back to segmentation.
The principal result of my investigation is that a uniform developmental principle controls the individual elementary units of all organisms, analogous to the finding that crystals are formed by the same laws in spite of the diversity of their forms.
A DNA sequence for the genome of bacteriophage ΦX174 of approximately 5,375 nucleotides has been determined using the rapid and simple 'plus and minus' method. The sequence identifies many of the features responsible for the production of the proteins of the nine known genes of the organism, including initiation and termination sites for the proteins and RNAs. Two pairs of genes are coded by the same region of DNA using different reading frames.
For it is not cell nuclei, not even individual chromosomes, but certain parts of certain chromosomes from certain cells that must be isolated and collected in enormous quantities for analysis; that would be the precondition for placing the chemist in such a position as would allow him to analyse [the hereditary material] more minutely than [can] the morphologists ... For the morphology of the nucleus has reference at the very least to the gearing of the clock, but at best the chemistry of the nucleus refers only to the metal from which the gears are formed.
My laboratory is interested in the related challenges of understanding the origin of life on the early earth, and constructing synthetic cellular life in the laboratory. Focusing on artificial life frees us to explore novel chemical systems, but what we learn from these systems helps us to understand possible pathways leading to the origin of life. Our basic design for a synthetic cell involves the encapsulation of a spontaneously replicating nucleic acid, which acts as the genetic material, within a spontaneously replicating membrane vesicle, which provides spatial localization. We are using chemical synthesis to make nucleic acids with modified nucleobases and sugar-phosphate backbones.
Were it not for the melanin in our skin, myoglobin in our muscles and haemoglobin in our blood, we would be the colour of mitochondria. And, if this were so, we would change colour when we exercised or ran out of breath, so that you could tell how energized someone was from his or her colour.