We pass through this world but once. Few tragedies can be more extensive than the stunting of life, few injustices deeper than the denial of an opportunity to strive or even to hope, by a limit imposed from without, but falsely identified as lying within.

We have become, by the power of a glorious evolutionary accident called intelligence, the stewards of life's continuity on earth. We did not ask for this role, but we cannot abjure it. We may not be suited to it, but here we are.

Skepticism is the agent of reason against organized irrationalism--and is therefore one of the keys to human social and civic decency.

We reveal ourselves in the metaphors we choose for depicting the cosmos in miniature.

Scientists have power by virtue of the respect commanded by the discipline... We live with poets and politicians, preachers and philosophers. All have their ways of knowing, and all are valid in their proper domain. The world is too complex and interesting for one way to hold all the answers.

We are here because one odd group of fishes had a peculiar fin anatomy that could transform into legs for terrestrial creatures; because the earth never froze entirely during an ice age; because a small and tenuous species, arising in Africa a quarter of a million years ago, has managed, so far, to survive by hook and by crook. We may yearn for a ‘higher answer’– but none exists

Science is not a heartless pursuit of objective information it is a creative human activity.

The human mind delights in finding pattern—so much so that we often mistake coincidence or forced analogy for profound meaning. No other habit of thought lies so deeply within the soul of a small creature trying to make sense of a complex world not constructed for it.

I had learned that a dexterous, opposable thumb stood among the hallmarks of human success. We had maintained, even exaggerated, this important flexibility of our primate forebears, while most mammals had sacrificed it in specializing their digits. Carnivores run, stab, and scratch. My cat may manipulate me psychologically, but he'll never type or play the piano.

My potential salvation...must remain an unswerving commitment to treat generality only as it emerges from little things that arrest us and open our eyes with "aha" -- while direct, abstract, learned assaults upon generalities usually glaze them over.

No Geologist worth anything is permanently bound to a desk or laboratory, but the charming notion that true science can only be based on unbiased observation of nature in the raw is mythology. Creative work, in geology and anywhere else, is interaction and synthesis: half-baked ideas from a bar room, rocks in the field, chains of thought from lonely walks, numbers squeezed from rocks in a laboratory, numbers from a calculator riveted to a desk, fancy equipment usually malfunctioning on expensive ships, cheap equipment in the human cranium, arguments before a road cut.

We are the offspring of history, and must establish our own paths in this most diverse and interesting of conceivable universes—one indifferent to our suffering, and therefore offering us maximum freedom to thrive, or to fail, in our own chosen way.

Bless all the women of this world who nurture our heritage while too many man rush off to kill for ideals that might now be deeply and personally held, but will often be viewed as repugnant by later generations.

The facts of nature are what they are, but we can only view them through the spectacles of our mind. Our mind works largely by metaphor and comparison, not always (or often) by relentless logic. When we are caught in conceptual traps, the best exit is often a change in metaphor — not because the new guideline will be truer to nature (for neither the old nor the new metaphor lies “out there” in the woods), but because we need a shift to more fruitful perspectives, and metaphor is often the best agent of conceptual transition.

Why should our nastiness be the baggage of an apish past and our kindness uniquely human? Why should we not seek continuity with other animals for our 'noble' traits as well?

I remember when we found the first population of living Cerion agassizi in central Eleuthera. Our hypothesis of Cerion's general pattern required that two predictions be affirmed (or else we were in trouble): this population must disappear by hybridization with mottled shells toward bank-interior coasts and with ribby snails toward the bank-edge. We hiked west toward the bank-interior and easily found hybrids right on the verge of the airport road. We then moved east toward the bank-edge along a disused road with vegetation rising to five feet in the center between the tire paths. We should have found our hybrids but we did not. The Cerion agassizi simply stopped about two hundred yards north of our first ribby Cerion. Then we realized that a pond lay just to our east and that ribby forms, with their coastal preferences, might not favor the western side of the pond. We forded the pond and found a classic hybrid zone between Cerion agassizi and ribby Cerions. (Ribby Cerion had just managed to round the south end of the pond, but had not moved sufficiently north along the west side to establish contact with C. agassizi populations.) I wanted to shout for joy. Then I thought, "But who can I tell; who cares?" And I answered myself, "I don't have to tell anyone. We have just seen and understood something that no one has ever seen and understood before. What more does a man need?

There are no shortcuts to moral insight. Nature is not intrinsically anything that can offer comfort or solace in human terms -- if only because our species is such an insignificant latecomer in a world not constructed for us. So much the better. The answers to moral dilemmas are not lying out there, waiting to be discovered. They reside, like the kingdom of God, within us -- the most difficult and inaccessible spot for any discovery or consensus.

Science tries to record and explain the factual character of the natural world, whereas religion struggles with spiritual and ethical questions about the meaning and proper conduct of our lives. The facts of nature simply cannot dictate correct moral behavior or spiritual meaning.

Obsolescence is a fate devoutly to be wished, lest science stagnate and die.

Current utility and historical origin are different subjects.

Our planet is not fragile at its own timescale and we, pitiful latecomers in the last microsecond of our planetary year, are stewards of nothing in the long run.

The idea of decimation as a lottery converts the new iconography of the Burgess Shale into a radical view about the pathways of life and the nature of history. ... May our poor and improbable species find joy in its new-found fragility and good fortune! Wouldn't anyone with the slightest sense of adventure, or the most weakly flickering respect for intellect, gladly exchange the old cosmic comfort for a look at something so weird and wonderful - yet so real - as *Opabinia*?

This new consensus seemed so compelling that Ernst Mayr, the dean of modern Darwinians, opened the ashcan of history for a deposit of Geoffrey's ideas about anatomical unity.

Objectivity cannot be equated with mental blankness; rather, objectivity resides in recognizing your preferences and then subjecting them to especially harsh scrutiny — and also in a willingness to revise or abandon your theories when the tests fail (as they usually do).

I am, somehow, less interested in the weight and convolutions of Einstein’s brain than in the near certainty that people of equal talent have lived and died in cotton fields and sweatshops.

Revolutions usually begin as replacements for older certainties, and not as pristine discoveries in uncharted terrain.

People, as curious primates, dote on concrete objects that can be seen and fondled. God dwells among the details, not in the realm of pure generality. We must tackle and grasp the larger, encompassing themes of our universe, but we make our best approach through small curiosities that rivet our attention - all those pretty pebbles on the shoreline of knowledge. For the ocean of truth washes over the pebbles with every wave, and they rattle and clink with the most wondrous din.