Certainly the most destructive vice if you like, that a person can have. More than pride, which is supposedly the number one of the cardinal sins - is self pity. Self pity is the worst possible emotion anyone can have. And the most destructive. It is, to slightly paraphrase what Wilde said about hatred, and I think actually hatred's a subset of self pity and not the other way around - ' It destroys everything around it, except itself '. Self pity will destroy relationships, it'll destroy anything that's good, it will fulfill all the prophecies it makes and leave only itself. And it's so simple to imagine that one is hard done by, and that things are unfair, and that one is underappreciated, and that if only one had had a chance at this, only one had had a chance at that, things would have gone better, you would be happier if only this, that one is unlucky. All those things. And some of them may well even be true. But, to pity oneself as a result of them is to do oneself an enormous disservice.I think it's one of things we find unattractive about the american culture, a culture which I find mostly, extremely attractive, and I like americans and I love being in america. But, just occasionally there will be some example of the absolutely ravening self pity that they are capable of, and you see it in their talk shows. It's an appalling spectacle, and it's so self destructive. I almost once wanted to publish a self help book saying 'How To Be Happy by Stephen Fry : Guaranteed success'. And people buy this huge book and it's all blank pages, and the first page would just say - ' Stop Feeling Sorry For Yourself - And you will be happy '. Use the rest of the book to write down your interesting thoughts and drawings, and that's what the book would be, and it would be true. And it sounds like 'Oh that's so simple', because it's not simple to stop feeling sorry for yourself, it's bloody hard. Because we do feel sorry for ourselves, it's what Genesis is all about.

The uncomfortable, as well as the miraculous, fact about the human mind is how it varies from individual to individual. The process of treatment can therefore be long and complicated. Finding the right balance of drugs, whether lithium salts, anti-psychotics, SSRIs or other kinds of treatment can be a very hit or miss heuristic process requiring great patience and classy, caring doctoring. Some patients would rather reject the chemical path and look for ways of using diet, exercise and talk-therapy. For some the condition is so bad that ECT is indicated. One of my best friends regularly goes to a clinic for doses of electroconvulsive therapy, a treatment looked on by many as a kind of horrific torture that isn’t even understood by those who administer it. This friend of mine is just about one of the most intelligent people I have ever met and she says, “I know. It ought to be wrong. But it works. It makes me feel better. I sometimes forget my own name, but it makes me happier. It’s the only thing that works.” For her. Lord knows, I’m not a doctor, and I don’t understand the brain or the mind anything like enough to presume to judge or know better than any other semi-informed individual, but if it works for her…. well then, it works for her. Which is not to say that it will work for you, for me or for others.