Nature might be a great experimentalist, but one who would never pass muster with an ethics review board – contravening the Helsinki Declaration and every norm of moral decency, left, right, and center.

Any death prior to the heat death of the universe is premature if your life is good.

Far from being the smartest possible biological species, we are probably better thought of as the stupidest possible biological species capable of starting a technological civilization - a niche we filled because we got there first, not because we are in any sense optimally adapted to it.

A full-throttled deployment of the practices of strategic communication would kill candor and leave truth bereft to fend for herself in the backstabbing night of political bogeys.

Our approach to existential risks cannot be one of trial-and-error. There is no opportunity to learn from errors. The reactive approach — see what happens, limit damages, and learn from experience — is unworkable. Rather, we must take a proactive approach. This requires foresight to anticipate new types of threats and a willingness to take decisive preventive action and to bear the costs (moral and economic) of such actions.

Think of a "discovery" as an act that moves the arrival of information from a later point in time to an earlier time. The discovery's value does not equal the value of the information discovered but rather the value of having the information available earlier than it otherwise would have been. A scientist or a mathematician may show great skill by being the first to find a solution that has eluded many others; yet if the problem would soon have been solved anyway, then the work probably has not much benefited the world [unless having a solution even slightly sooner is immensely valuable or enables further important and urgent work].